{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:03:47Z","timestamp":1756339427574,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,11,18]]},"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:p>Leydig cell tumours (LCTs) of the ovary are rare ovarian tumours that usually present with hyperandrogenism. Conventional radiological imagings are helpful in localising these tumours. However, some tumours may be too small to be localised before curative surgical removal. It is important to identify these androgen-secreting neoplasms which originate mostly from adrenals or ovaries because they are potentially malignant and require specific treatment. When conventional imagings are unrevealing, selective ovarian and adrenal venous sampling (SOAVS) is the next option. We report a case of LCT that was localised by SOAVS after results from other imaging modalities remained inconclusive.<\/jats:p>","DOI":"10.1136\/bcr-2020-238012","type":"journal-article","created":{"date-parts":[[2020,12,13]],"date-time":"2020-12-13T23:30:51Z","timestamp":1607902251000},"page":"e238012","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Hyperandrogenism caused by ovarian Leydig cell tumour: finding the needle in a haystack"],"prefix":"10.1136","volume":"13","author":[{"given":"Chin Voon","family":"Tong","sequence":"first","affiliation":[{"name":"Medicine, Hospital Melaka, Bandar Melaka, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong Ting","family":"Tai","sequence":"additional","affiliation":[{"name":"Medicine, Hospital Melaka, Bandar Melaka, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,12,13]]},"reference":[{"key":"2025082702475490000_13.12.e238012.1","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1001\/jamadermatol.2016.0358","article-title":"Clinician vs self-ratings of hirsutism in patients with polycystic ovarian syndrome: associations with quality of life and depression","volume":"152","author":"Pasch","year":"2016","journal-title":"JAMA Dermatol"},{"key":"2025082702475490000_13.12.e238012.2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp033496"},{"key":"2025082702475490000_13.12.e238012.3","doi-asserted-by":"crossref","unstructured":"Pugeat Raverot M M , Plotton I , et al . Androgen-secreting adrenal and ovarian neoplasms. In: Azziz R , Nestler JE , Dewailly D , et al , eds. Androgen excess disorders in women. contemporary endocrinology. 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