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Early recognition and initiation of treatment are vital. Furthermore, the patient had been diagnosed with schizophrenia over a decade previously and more recently started on sodium valproate, a medication known to contribute to hyperammonaemia. This case also emphasises the importance of exclusion of underlying organic disease prior to diagnosis of psychiatric conditions.<\/jats:p>","DOI":"10.1136\/bcr-2020-238023","type":"journal-article","created":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T12:06:39Z","timestamp":1622462799000},"page":"e238023","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Status epilepticus secondary to hyperammonaemia: a late presentation of an undiagnosed urea cycle defect"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2179-8907","authenticated-orcid":false,"given":"Penelope","family":"Beddoes","sequence":"first","affiliation":[{"name":"Critical Care and Anaesthetics, Whipps Cross University Hospital NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriela","family":"Nerone","sequence":"additional","affiliation":[{"name":"Critical Care and Anaesthetics, Whipps Cross University Hospital NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2234-8409","authenticated-orcid":false,"given":"Charlotte","family":"Tai","sequence":"additional","affiliation":[{"name":"Critical Care and Anaesthetics, Whipps Cross University Hospital NHS Trust, London, UK"},{"name":"Respiratory Medicine, Saint Bartholomew's Hospital Barts Heart Centre, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,5,31]]},"reference":[{"key":"2025082802415748000_14.5.e238023.1","doi-asserted-by":"publisher","DOI":"10.1067\/mem.2002.122057"},{"key":"2025082802415748000_14.5.e238023.2","doi-asserted-by":"publisher","DOI":"10.1136\/emj.2004.015651"},{"key":"2025082802415748000_14.5.e238023.3","unstructured":". 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