{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T08:14:44Z","timestamp":1780992884994,"version":"3.54.1"},"reference-count":11,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,12,19]]},"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>A 49-year-old Asian Indian woman, with a previous history of biopsy proven stage IV primary lung adenocarcinoma with metastasis to liver, bones and central nervous system, presented with 1-month history of photopsia in right eye. She was on oral erlotinib since 6 months. Dilated fundus examination of right eye revealed a solitary dome-shaped brownish elevated lesion of approximately 1-disc diameter along the inferotemporal midperiphery with surrounding areas of hypopigmentation. Based on multimodal imaging, a diagnosis of resolved solitary unilateral choroidal metastasis from lung carcinoma in the right eye was made. In view of inactive and regressed choroidal metastasis, no intervention was mandated.<\/jats:p>","DOI":"10.1136\/bcr-2020-238131","type":"journal-article","created":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T12:02:12Z","timestamp":1610971332000},"page":"e238131","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Incidental finding of regressed solitary unilateral choroidal metastasis from lung adenocarcinoma with EGFR exon-19 deletion treated with erlotinib"],"prefix":"10.1136","volume":"14","author":[{"given":"Srikanta Kumar","family":"Padhy","sequence":"first","affiliation":[{"name":"Retina, Uvea and ROP Services, LV Prasad Eye Institute Bhubaneswar Campus, Bhubaneswar, Orissa, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0800-9961","authenticated-orcid":false,"given":"Swathi","family":"Kaliki","sequence":"additional","affiliation":[{"name":"Ocular Oncology, LV Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,1,18]]},"reference":[{"key":"2025082800034283000_14.1.e238131.1","doi-asserted-by":"crossref","first-page":"122","DOI":"10.4103\/0301-4738.154380","article-title":"Choroidal metastases: origin, features, and therapy","volume":"63","author":"Arepalli","year":"2015","journal-title":"Indian J Ophthalmol"},{"key":"2025082800034283000_14.1.e238131.2","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.preteyeres.2018.09.003","article-title":"New concepts in the diagnosis and management of choroidal metastases","volume":"68","author":"Mathis","year":"2019","journal-title":"Prog Retin Eye Res"},{"key":"2025082800034283000_14.1.e238131.3","doi-asserted-by":"crossref","first-page":"122","DOI":"10.4103\/1119-0388.218213","article-title":"Choroidal metastasis: a review of literature","volume":"20","author":"S","year":"2017","journal-title":"Trop J Med Res"},{"key":"2025082800034283000_14.1.e238131.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(97)30148-1"},{"key":"2025082800034283000_14.1.e238131.5","doi-asserted-by":"crossref","first-page":"75","DOI":"10.4103\/0974-620X.137159","article-title":"Rapid regression of choroidal metastasis from lung cancer using erlotinib (Tarceva)","volume":"7","author":"Ye","year":"2014","journal-title":"Oman J Ophthalmol"},{"key":"2025082800034283000_14.1.e238131.6","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1038\/eye.2000.215","article-title":"Solitary choroidal metastasis managed by transpupillary thermotherapy","volume":"14 Pt 5","author":"Kiratli","year":"2000","journal-title":"Eye"},{"key":"2025082800034283000_14.1.e238131.7","doi-asserted-by":"publisher","DOI":"10.1097\/IAE.0000000000000131"},{"key":"2025082800034283000_14.1.e238131.8","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/s10792-008-9234-2","article-title":"Autofluorescence of metastatic choroidal tumor","volume":"29","author":"Ishida","year":"2009","journal-title":"Int Ophthalmol"},{"key":"2025082800034283000_14.1.e238131.9","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1097\/ICU.0b013e32835f8ba1","article-title":"Autofluorescence of intraocular tumours","volume":"24","author":"Almeida","year":"2013","journal-title":"Curr Opin Ophthalmol"},{"key":"2025082800034283000_14.1.e238131.10","unstructured":"Shields JA , Shields CL . Metastatic tumors to the intraocular structures. In: Intraocular tumors. An atlas and textbook. 2nd. Philadelphia: Lippincott Williams and Wilkins, 2008: 198\u2013227."},{"key":"2025082800034283000_14.1.e238131.11","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1159\/000448114","article-title":"Tyrosine kinase inhibitors in the treatment of choroidal metastases from non-small-cell lung cancer: a case report and review of literature","volume":"3","author":"Nair","year":"2017","journal-title":"Ocul Oncol Pathol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-238131","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:03:55Z","timestamp":1756364635000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-238131"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":11,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,1,18]]},"published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1136\/bcr-2020-238131"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-238131","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}