{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T00:57:36Z","timestamp":1778547456620,"version":"3.51.4"},"reference-count":19,"publisher":"BMJ","issue":"1","funder":[{"DOI":"10.13039\/501100013342","name":"NIHR Imperial Biomedical Research Centre","doi-asserted-by":"publisher","award":["P68495"],"award-info":[{"award-number":["P68495"]}],"id":[{"id":"10.13039\/501100013342","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,12,17]]},"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>We present two unusual presentations of extrapulmonary tuberculosis (EPTB) and more specifically intra-abdominal tuberculosis (TB). These cases were initially suspicious for ovarian cancer, presenting with non-specific symptoms, ultrasound-confirmed ascites and elevated cancer antigen 125 tumour marker (CA 125). However, in both cases chest imaging demonstrated enlarged mediastinal nodes amenable to endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA), which confirmed the diagnosis of TB. Both cases were successfully treated with quadruple TB therapy.<\/jats:p>","DOI":"10.1136\/bcr-2020-238199","type":"journal-article","created":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T12:17:48Z","timestamp":1610972268000},"page":"e238199","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["CA 125 and TB"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7015-5943","authenticated-orcid":false,"given":"Mirae","family":"Park","sequence":"first","affiliation":[{"name":"Imperial Clinical Respiratory Research Unit, Imperial College Healthcare NHS Trust, London, UK"},{"name":"Faculty of Medicine, National Heart and Lung Institute, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ranju","family":"Dhawan","sequence":"additional","affiliation":[{"name":"Department of Imaging and Radiology, Imperial College Healthcare NHS Trust, London, UK"},{"name":"Hybrid Imaging & Therapy Unit, Wellington Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Whittaker","sequence":"additional","affiliation":[{"name":"Paediatric Infectious Diseases and Immunology, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Onn Min","family":"Kon","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, National Heart and Lung Institute, London, UK"},{"name":"Respiratory Medicine, Imperial College Healthcare NHS Trust, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,1,18]]},"reference":[{"key":"2025082703575333000_14.1.e238199.1","unstructured":"WHO . Global tuberculosis report 2019, 2019. Available: http:\/\/apps.who.int\/bookorders [Accessed 29 Nov 2019]."},{"key":"2025082703575333000_14.1.e238199.2","doi-asserted-by":"crossref","first-page":"e898","DOI":"10.1016\/S2214-109X(17)30289-9","article-title":"The global burden of tuberculosis mortality in children: a mathematical modelling study","volume":"5","author":"Dodd","year":"2017","journal-title":"Lancet Glob Health"},{"key":"2025082703575333000_14.1.e238199.3","unstructured":"Public Health England . Tuberculosis in England 2019 report (presenting data to end of 2018). Version 1. Public Health England, 2019."},{"key":"2025082703575333000_14.1.e238199.4","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1097\/INF.0000000000001270","article-title":"Pediatric extrapulmonary tuberculosis: clinical spectrum, risk factors and diagnostic challenges in a low prevalence region","volume":"35","author":"Santiago-Garc\u00eda","year":"2016","journal-title":"Pediatr Infect Dis J"},{"key":"2025082703575333000_14.1.e238199.5","doi-asserted-by":"publisher","DOI":"10.1086\/380644"},{"key":"2025082703575333000_14.1.e238199.6","first-page":"1178","article-title":"Extra-pulmonary manifestations in a large metropolitan area with a low incidence of tuberculosis","volume":"7","author":"Gonzalez","year":"2003","journal-title":"Int J Tuberc Lung Dis"},{"key":"2025082703575333000_14.1.e238199.7","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2004.018077"},{"key":"2025082703575333000_14.1.e238199.8","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1385\/MO:18:4:289","article-title":"Elevated serum cancer antigen 125 levels in advanced abdominal tuberculosis","volume":"18","author":"Thakur","year":"2001","journal-title":"Med Oncol"},{"key":"2025082703575333000_14.1.e238199.9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2012\/215293","article-title":"TB peritonitis mistaken for ovarian carcinomatosis based on an elevated CA-125","volume":"2012","author":"Boss","year":"2012","journal-title":"Case Rep Med"},{"key":"2025082703575333000_14.1.e238199.10","doi-asserted-by":"crossref","DOI":"10.3349\/ymj.2013.54.5.1241","article-title":"Clinical significance of serum CA-125 in Korean females with ascites","volume":"54","author":"Bae","year":"2013","journal-title":"Yonsei Med J"},{"key":"2025082703575333000_14.1.e238199.11","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.tube.2012.10.014","article-title":"The clinical significance of CA-125 in pulmonary tuberculosis","volume":"93","author":"Kim","year":"2013","journal-title":"Tuberculosis"},{"key":"2025082703575333000_14.1.e238199.12","doi-asserted-by":"publisher","DOI":"10.1159\/000050303"},{"key":"2025082703575333000_14.1.e238199.13","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2011-200063"},{"key":"2025082703575333000_14.1.e238199.14","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00901-2017"},{"key":"2025082703575333000_14.1.e238199.15","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-004-0831-0"},{"key":"2025082703575333000_14.1.e238199.16","doi-asserted-by":"crossref","unstructured":"Kaushik R , Sagar S , Mital M . Radiological spectrum of infectious sacroiliitis: a retrospective, study of 40 adults. Ind J Appl Res;9.doi:10.36106\/ijar","DOI":"10.36106\/ijar"},{"key":"2025082703575333000_14.1.e238199.17","first-page":"134","article-title":"[Clinical and imaging characteristics of 110 patients with infectious sacroiliitis]","volume":"59","author":"Wang","year":"2020","journal-title":"Zhonghua Nei Ke Za Zhi"},{"key":"2025082703575333000_14.1.e238199.18","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.2214\/AJR.14.14217","article-title":"Unilateral sacroiliitis: differential diagnosis between infectious sacroiliitis and spondyloarthritis based on MRI findings","volume":"205","author":"Kang","year":"2015","journal-title":"AJR Am J Roentgenol"},{"key":"2025082703575333000_14.1.e238199.19","unstructured":"Shah AR , Nagraj HAS . Unilateral Acute Sacroiliitis - Think Infection. No Injection! ECR 2019.doi:10.26044\/ecr2019\/C-3035"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-238199","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:58:00Z","timestamp":1756292280000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-238199"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":19,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,1,18]]},"published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1136\/bcr-2020-238199"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-238199","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}