{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:36:05Z","timestamp":1787016965525,"version":"build-2736575974"},"reference-count":20,"publisher":"BMJ","issue":"12","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,11,11]]},"published-print":{"date-parts":[[2020,12]]},"abstract":"<jats:p>\n                    Although uncommon,\n                    <jats:italic>Brucella<\/jats:italic>\n                    infection can occur outside the areas of high endemicity, such as the USA. In the southern USA, hunters of wild swine are at risk for brucellosis. We present a case of a patient with fever, headache and constitutional symptoms that were ongoing for 11 months. He was diagnosed with neurobrucellosis. The patient was treated successfully with intravenous ceftriaxone, oral doxycycline and oral rifampin therapy. He had persistent neurological sequelae after completing treatment. This case illustrates the high index of suspicion needed to diagnose neurobrucellosis in a non-endemic country because initial symptoms can be subtle. The disease can be treated successfully, but long-lasting neurological sequelae are common.\n                  <\/jats:p>","DOI":"10.1136\/bcr-2020-238216","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T18:18:21Z","timestamp":1608661101000},"page":"e238216","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Neurobrucellosis associated with feral swine hunting in the southern United States"],"prefix":"10.1136","volume":"13","author":[{"given":"Harry Ross","family":"Powers","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Mayo Clinic, Jacksonville, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jared R","family":"Nelson","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Mayo Clinic, Jacksonville, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salvador","family":"Alvarez","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Mayo Clinic, Jacksonville, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julio C","family":"Mendez","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Mayo Clinic, Jacksonville, Florida, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2020,12,21]]},"reference":[{"key":"2025082703213059000_13.12.e238216.1","unstructured":"Lindquist D , Chu M , Probert W . Francisella and brucella. In: Murray PR , Baron E , Landry ML , et al , eds. Manual of clinical microbiology. 9th ed. Washington, (DC): ASM Press, 2007: 824."},{"key":"2025082703213059000_13.12.e238216.2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0001865"},{"key":"2025082703213059000_13.12.e238216.3","unstructured":"Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases, Division of High-Consequence Pathogens and Pathology . Brucellosis surveillance. Atlanta (GA): Centers for disease control and prevention, 2012. https:\/\/www.cdc.gov\/brucellosis\/resources\/surveillance.html"},{"key":"2025082703213059000_13.12.e238216.4","first-page":"618","article-title":"Brucella suis infection associated with feral swine hunting - three states, 2007-2008","volume":"58","year":"2009","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"2025082703213059000_13.12.e238216.5","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.42.1.378-379.2004"},{"key":"2025082703213059000_13.12.e238216.6","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12478"},{"key":"2025082703213059000_13.12.e238216.7","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00007814"},{"key":"2025082703213059000_13.12.e238216.8","unstructured":"Centers for Disease Control and Prevention, National Center for Emerging and Zoonotic Infectious Diseases, Division of High-Consequence Pathogens and Pathology . Brucellosis reference guide: exposures, testing, and prevention. Atlanta (GA): Centers for Disease Control and Prevention, 2017. https:\/\/stacks.cdc.gov\/view\/cdc\/46133"},{"key":"2025082703213059000_13.12.e238216.9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.vetmic.2013.02.025","article-title":"Feral swine brucellosis in the United States and prospective genomic techniques for disease epidemiology","volume":"166","author":"Leiser","year":"2013","journal-title":"Vet Microbiol"},{"key":"2025082703213059000_13.12.e238216.10","unstructured":"Centers for Disease Control and Prevention . Feral swine hunters: protect yourself and your family from brucellosis. Atlanta (GA): Centers for Disease Control and Prevention, 2015. https:\/\/www.aphis.usda.gov\/publications\/animal_health\/2015\/bro_cdc_feral_swine.pdf"},{"key":"2025082703213059000_13.12.e238216.11","unstructured":"Centers for Disease Control and Prevention, Office of Public Health Scientific Services . Brucellosis (Brucella spp.) 2010 case definition. Atlanta (GA): centers for disease control and prevention, 2010. Available: https:\/\/wwwn.cdc.gov\/nndss\/conditions\/brucellosis\/case-definition\/2010\/ [Accessed 25 June 2020]."},{"key":"2025082703213059000_13.12.e238216.12","doi-asserted-by":"crossref","first-page":"408","DOI":"10.5455\/msm.2016.28.408-411","article-title":"Clinical manifestations in 82 neurobrucellosis patients from Kosovo","volume":"28","author":"Dreshaj","year":"2016","journal-title":"Mater Sociomed"},{"key":"2025082703213059000_13.12.e238216.13","doi-asserted-by":"publisher","DOI":"10.1590\/S1413-86702011000100010"},{"key":"2025082703213059000_13.12.e238216.14","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cit072"},{"key":"2025082703213059000_13.12.e238216.15","doi-asserted-by":"publisher","DOI":"10.1016\/S0732-8893(02)00426-1"},{"key":"2025082703213059000_13.12.e238216.16","first-page":"395","article-title":"Neurobrucellosis: clinical and neuroimaging correlation","volume":"25","author":"Al-Sous","year":"2004","journal-title":"AJNR Am J Neuroradiol"},{"key":"2025082703213059000_13.12.e238216.17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2005.10.029"},{"key":"2025082703213059000_13.12.e238216.18","doi-asserted-by":"publisher","DOI":"10.3109\/13550280903586386"},{"key":"2025082703213059000_13.12.e238216.19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0040317"},{"key":"2025082703213059000_13.12.e238216.20","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.05974-11"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-238216","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T10:21:38Z","timestamp":1756290098000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-238216"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12]]},"references-count":20,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2020,12,21]]},"published-print":{"date-parts":[[2020,12]]}},"alternative-id":["10.1136\/bcr-2020-238216"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-238216","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12]]}}}