{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:36:45Z","timestamp":1792085805256,"version":"4.4.0"},"reference-count":17,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,2,2]]},"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:p>Neutropenic enterocolitis (NEC) is a life-threatening bowel condition, usually resulting from chemotherapy, with a mortality rate thought to be as high as 50%. Markers of poor prognosis include gastrointestinal perforation and bowel wall thickness radiologically detected to be greater than 10 mm. NEC is associated with severe neutropenia and predominantly affects the large bowel; however, we present a case of severe NEC with oesophageal perforation requiring transfer to a specialist upper gastrointestinal unit for corrective stenting. Despite initial bowel wall thickness of 20 mm in the ascending colon, two discrete episodes of bowel perforation and an inpatient stay totalling 89 days, the patient was discharged with full independence, a good quality of life and a plan for curative mastectomy plus axillary clearance.<\/jats:p>","DOI":"10.1136\/bcr-2020-238277","type":"journal-article","created":{"date-parts":[[2021,3,2]],"date-time":"2021-03-02T10:56:20Z","timestamp":1614682580000},"page":"e238277","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Good functional outcome following severe neutropenic enterocolitis and perforation in a 48-year-old woman undergoing chemotherapy for breast cancer"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5088-1991","authenticated-orcid":false,"given":"Richard","family":"Fenton","sequence":"first","affiliation":[{"name":"Anaesthetics, Southmead Hospital, Bristol, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hannah","family":"Schneiders","sequence":"additional","affiliation":[{"name":"ICU, Yeovil District Hospital NHS Foundation Trust, Yeovil, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremy","family":"Reid","sequence":"additional","affiliation":[{"name":"Anaesthesia, Yeovil District Hospital, Yeovil, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,3,2]]},"reference":[{"key":"2025082802524361000_14.3.e238277.1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2005.00442.x"},{"key":"2025082802524361000_14.3.e238277.2","doi-asserted-by":"crossref","first-page":"42","DOI":"10.3748\/wjg.v23.i1.42","article-title":"Neutropenic enterocolitis","volume":"23","author":"Rodrigues","year":"2017","journal-title":"World J Gastroenterol"},{"key":"2025082802524361000_14.3.e238277.3","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1097\/DCR.0000000000001548","article-title":"Neutropenic enterocolitis: clinical features and outcomes","volume":"63","author":"Abu-Sbeih","year":"2020","journal-title":"Dis Colon Rectum"},{"key":"2025082802524361000_14.3.e238277.4","doi-asserted-by":"crossref","first-page":"36","DOI":"10.4291\/wjgp.v10.i3.36","article-title":"Neutropenic enterocolitis: a clinico-pathological review","volume":"10","author":"Xia","year":"2019","journal-title":"World J Gastrointest Pathophysiol"},{"key":"2025082802524361000_14.3.e238277.5","doi-asserted-by":"crossref","DOI":"10.1093\/omcr\/omz140","article-title":"Chemotherapy-associated neutropenic enterocolitis of the transverse colon post right hemicolectomy","volume":"2020","author":"Principe","year":"2020","journal-title":"Oxf Med Case Reports"},{"key":"2025082802524361000_14.3.e238277.6","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2263011932"},{"key":"2025082802524361000_14.3.e238277.7","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2009.03.002"},{"key":"2025082802524361000_14.3.e238277.8","unstructured":"Qasim A , Nahas J . Neutropenic enterocolitis (typhlitis). StatPearls [Internet], 2020. Available: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK551577\/"},{"key":"2025082802524361000_14.3.e238277.9","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cis998"},{"key":"2025082802524361000_14.3.e238277.10","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1097\/PAS.0000000000000517","article-title":"Neutropenic enterocolitis","volume":"39","author":"Sachak","year":"2015","journal-title":"Am J Surg Pathol"},{"key":"2025082802524361000_14.3.e238277.11","doi-asserted-by":"publisher","DOI":"10.1086\/514946"},{"key":"2025082802524361000_14.3.e238277.12","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(79)90483-2"},{"key":"2025082802524361000_14.3.e238277.13","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1200\/JCO.2001.19.3.756","article-title":"Neutropenic enterocolitis in patients with acute leukemia: prognostic significance of bowel wall thickening detected by ultrasonography","volume":"19","author":"Cartoni","year":"2001","journal-title":"J Clin Oncol"},{"key":"2025082802524361000_14.3.e238277.14","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197902)43:2<695::AID-CNCR2820430242>3.0.CO;2-9"},{"key":"2025082802524361000_14.3.e238277.15","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-300563"},{"key":"2025082802524361000_14.3.e238277.16","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1097\/CCM.0000000000003687","article-title":"Neutropenic enterocolitis in critically ill patients: spectrum of the disease and risk of invasive fungal disease","volume":"47","author":"Duceau","year":"2019","journal-title":"Crit Care Med"},{"key":"2025082802524361000_14.3.e238277.17","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19860201)57:3<603::AID-CNCR2820570335>3.0.CO;2-K"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-238277","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:52:52Z","timestamp":1756374772000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-238277"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":17,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,3,2]]},"published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1136\/bcr-2020-238277"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-238277","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3]]}}}