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We have shown octreotide to be effective in improving the pathological effects of primary IL, associated with improved clinical well-being and serology, but it is not a curative therapy.<\/jats:p>","DOI":"10.1136\/bcr-2020-238457","type":"journal-article","created":{"date-parts":[[2021,4,9]],"date-time":"2021-04-09T12:40:23Z","timestamp":1617972023000},"page":"e238457","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Refractory primary intestinal lymphangiectasia effectively managed with subcutaneous octreotide"],"prefix":"10.1136","volume":"14","author":[{"given":"Amir","family":"Halim","sequence":"first","affiliation":[{"name":"Gastroenterology, Epsom and Saint Helier University Hospitals NHS Trust, Epsom, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philippa","family":"Youd","sequence":"additional","affiliation":[{"name":"Gastroenterology, Epsom and Saint Helier University Hospitals NHS Trust, Epsom, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jill","family":"Thorpe","sequence":"additional","affiliation":[{"name":"Nutrition, Epsom and Saint Helier University Hospitals NHS Trust, Carshalton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irfan","family":"Halim","sequence":"additional","affiliation":[{"name":"General Surgery, Highgate Private Hospital, London, Highgate, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,4,9]]},"reference":[{"key":"2025082801412040000_14.4.e238457.1","doi-asserted-by":"crossref","first-page":"512","DOI":"10.12659\/AJCR.899636","article-title":"Intestinal lymphangiectasia: insights on management and literature review","volume":"17","author":"Alshikho","year":"2016","journal-title":"Am J Case Rep"},{"key":"2025082801412040000_14.4.e238457.2","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000002849","article-title":"Primary intestinal lymphangiectasia manifested as unusual edemas and effusions: a case report","volume":"95","author":"Wang","year":"2016","journal-title":"Medicine"},{"key":"2025082801412040000_14.4.e238457.3","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1172-3-5"},{"key":"2025082801412040000_14.4.e238457.4","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0016-5085(19)35130-3","article-title":"The role of the gastrointestinal system in 'idiopathic hypoproteinemia'","volume":"41","author":"Waldmann","year":"1961","journal-title":"Gastroenterology"},{"key":"2025082801412040000_14.4.e238457.5","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/S0398-0499(04)96722-4","article-title":"Limb lymphedema as a first manifestation of primary intestinal lymphangiectasia (Waldmann's disease)","volume":"29","author":"Boursier","year":"2004","journal-title":"J Mal Vasc"},{"key":"2025082801412040000_14.4.e238457.6","doi-asserted-by":"crossref","first-page":"528","DOI":"10.12998\/wjcc.v2.i10.528","article-title":"Primary intestinal lymphangiectasia: minireview","volume":"2","author":"Ingle","year":"2014","journal-title":"World J Clin Cases"},{"key":"2025082801412040000_14.4.e238457.7","first-page":"576","article-title":"Surgical therapy of segmental jejunal, primary intestinal lymphangiectasia","volume":"51","author":"Kneist","year":"2013","journal-title":"Z Gastroenterol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-238457","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:41:27Z","timestamp":1756370487000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-238457"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":7,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,4,9]]},"published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1136\/bcr-2020-238457"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-238457","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4]]}}}