{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T05:23:24Z","timestamp":1787203404010,"version":"build-2736575974"},"reference-count":20,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2021,1,27]],"date-time":"2021-01-27T00:00:00Z","timestamp":1611705600000},"content-version":"unspecified","delay-in-days":26,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,12,30]]},"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>\n                    The clinical manifestation of\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    could vary from asymptomatic bacteraemia to systemic bloodstream infection and meningitis. We describe an unusual course of\n                    <jats:italic>E. coli<\/jats:italic>\n                    infection in twins, emphasising commencement of appropriate antimicrobial therapy. A set of male dichorionic diamniotic twins were delivered at 34 weeks of gestation by caesarian section. Pregnancy was complicated by diabetes, pre-eclampsia and cholestasis. Antenatal ultrasounds noted a congenital pulmonary airway malformation in twin A. Following delivery, twin A developed respiratory distress, but twin B was asymptomatic. Partial septic work-up at admission in the neonatal intensve care unit was done. Twin A\u2019s blood culture grew\n                    <jats:italic>E. coli<\/jats:italic>\n                    , while twin B\u2019s blood culture was negative. Twin A was treated with 7 days of intravenous antibiotics. At 11 days of age, twin B acutely developed a scrotal swelling. On suspicion of testicular torsion, he was taken for urgent surgery, which revealed a scrotal abscess positive for\n                    <jats:italic>E. coli<\/jats:italic>\n                    . The scrotum was irrigated and successfully treated with 4\u2009weeks of antibiotics. Both twins were doing well at 3 months of follow-up.\n                  <\/jats:p>","DOI":"10.1136\/bcr-2020-238470","type":"journal-article","created":{"date-parts":[[2021,1,27]],"date-time":"2021-01-27T12:35:13Z","timestamp":1611750913000},"page":"e238470","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Neonatal\n                    <i>Escherichia coli<\/i>\n                    infection in twins: clinical spectrum and management dilemma"],"prefix":"10.1136","volume":"14","author":[{"given":"Dylan","family":"Ehman","sequence":"first","affiliation":[{"name":"Royal University Hospital, Saskatoon, Saskatchewan, Canada"},{"name":"College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7697-0893","authenticated-orcid":false,"given":"Veronica","family":"Mugarab Samedi","sequence":"additional","affiliation":[{"name":"Royal University Hospital, Saskatoon, Saskatchewan, Canada"},{"name":"College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8378-0329","authenticated-orcid":false,"given":"Kaarthigeyan","family":"Kalaniti","sequence":"additional","affiliation":[{"name":"Royal University Hospital, Saskatoon, Saskatchewan, Canada"},{"name":"College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sibasis","family":"Daspal","sequence":"additional","affiliation":[{"name":"Royal University Hospital, Saskatoon, Saskatchewan, Canada"},{"name":"College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,1,27]]},"reference":[{"key":"2025082803241241000_14.1.e238470.1","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1093\/pch\/pxx023","article-title":"Management of term infants at increased risk for early-onset bacterial sepsis","volume":"22","author":"Jefferies","year":"2017","journal-title":"Paediatr Child Health"},{"key":"2025082803241241000_14.1.e238470.2","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1093\/pch\/pxz073","article-title":"Early-Onset neonatal sepsis: organism patterns between 2009 and 2014","volume":"25","author":"Sgro","year":"2020","journal-title":"Paediatr Child Health"},{"key":"2025082803241241000_14.1.e238470.3","doi-asserted-by":"crossref","unstructured":"American Academy of Pediatrics . Group B Streptococcal Infections. In: Kimberlin DW , Brady MT , Jackson MA , et al , eds. 2018 report of the Committee on infectious diseases. 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In: Kimberlin DW , Brady MT , Jackson MA , et al. , eds. 2018 report of the Committee on infectious diseases. Red Book, 2018: 328\u201331."},{"key":"2025082803241241000_14.1.e238470.8","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2006-0440"},{"key":"2025082803241241000_14.1.e238470.9","unstructured":"Elder JS . Disorders and Anomalies of the Scrotal Contents. In: Nelson textbook of pediatrics. 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