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This included intravenous steroids, nebulised epinephrine and intravenous antibiotics. After this initial treatment they both required investigation and optimisation of their underlying medical conditions (rheumatoid arthritis with possible systemic lupus erythematosus and nephrotic syndrome) as more definitive management.<\/jats:p>","DOI":"10.1136\/bcr-2020-238664","type":"journal-article","created":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T15:29:21Z","timestamp":1607527761000},"page":"e238664","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Non-infective supraglottitis: two cases of unusual aetiology"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3633-7206","authenticated-orcid":false,"given":"Olivia","family":"Kenyon","sequence":"first","affiliation":[{"name":"Department of ENT, Luton and Dunstable University Hospital, Luton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victoria","family":"Blackabey","sequence":"additional","affiliation":[{"name":"Department of ENT, Luton and Dunstable University Hospital, Luton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rishi","family":"Talwar","sequence":"additional","affiliation":[{"name":"Department of ENT, Luton and Dunstable University Hospital, Luton, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,12,9]]},"reference":[{"key":"2025082708542861000_13.12.e238664.1","first-page":"279","article-title":"Airway intervention in cases of acute epiglottitis","volume":"12","author":"Shimizu","year":"2016","journal-title":"B-ENT"},{"key":"2025082708542861000_13.12.e238664.2","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1017\/S0022215110002446","article-title":"Acute epiglottitis: epidemiology and Streptococcus pneumoniae serotype distribution in adults","volume":"125","author":"Isakson","year":"2011","journal-title":"J Laryngol Otol"},{"key":"2025082708542861000_13.12.e238664.3","doi-asserted-by":"crossref","first-page":"2183","DOI":"10.1002\/lary.21083","article-title":"Supraglottitis in the era following widespread immunization against Haemophilus influenzae type B: evolving principles in diagnosis and management","volume":"120","author":"Guardiani","year":"2010","journal-title":"Laryngoscope"},{"key":"2025082708542861000_13.12.e238664.4","doi-asserted-by":"publisher","DOI":"10.3399\/bjgp15X683653"},{"key":"2025082708542861000_13.12.e238664.5","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1016\/j.oraloncology.2012.02.023","article-title":"Laryngeal edema after radiotherapy in patients with squamous cell carcinomas of the larynx and hypopharynx","volume":"48","author":"Bae","year":"2012","journal-title":"Oral Oncol"},{"key":"2025082708542861000_13.12.e238664.6","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1186\/s13054-015-1018-2","article-title":"Postextubation laryngeal edema and stridor resulting in respiratory failure in critically ill adult patients: updated review","volume":"19","author":"Pluijms","year":"2015","journal-title":"Crit Care"},{"key":"2025082708542861000_13.12.e238664.7","doi-asserted-by":"crossref","first-page":"2473974X1880543","DOI":"10.1177\/2473974X18805431","article-title":"Angioedema involving the larynx after starting apixaban","volume":"3","author":"Williamson","year":"2019","journal-title":"OTO Open"},{"key":"2025082708542861000_13.12.e238664.8","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1016\/j.jvoice.2015.07.006","article-title":"Laryngeal side effects of tyrosine kinase inhibitors","volume":"30","author":"Ovnat Tamir","year":"2016","journal-title":"J Voice"},{"key":"2025082708542861000_13.12.e238664.9","doi-asserted-by":"crossref","first-page":"391","DOI":"10.12968\/hmed.2019.80.7.391","article-title":"Hereditary angioedema: an update on causes, manifestations and treatment","volume":"80","author":"Longhurst","year":"2019","journal-title":"Br J Hosp Med"},{"key":"2025082708542861000_13.12.e238664.10","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.jemermed.2013.08.033","article-title":"The heat is on\u2026 thermal epiglottitis as a late presentation of airway steam injury","volume":"46","author":"Kudchadkar","year":"2014","journal-title":"J Emerg Med"},{"key":"2025082708542861000_13.12.e238664.11","doi-asserted-by":"crossref","DOI":"10.1186\/s12871-018-0665-7","article-title":"Beware of thermal epiglottis! 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