{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:36:13Z","timestamp":1787016973930,"version":"build-2736575974"},"reference-count":18,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,1,23]]},"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:p>\n                    <jats:italic>Mycobacterium tuberculosis<\/jats:italic>\n                    (MTB) is an aerobic bacillus responsible for tuberculous infection. The the thyroid gland being affected by MTB is a rare condition. A 71-year-old woman had 6 months of slight cervical discomfort. Her neck ultrasound showed, at the right lobe of the thyroid, a dominant heterogeneous nodule of 18\u2009mm and homolateral lymph nodes with suspicious ultrasonographic features. The patient underwent fine-needle aspiration, the results of which were non-diagnostic (thyroid nodule) and reactive pattern (lymph node). A total thyroidectomy was performed and a lymph node was sampled for extemporaneous examination. Surprisingly, necrotising granulomas were documented. The diagnosis was definitely established by a positive culture of the lymph node tissue and molecular detection of MTB. Pulmonary involvement was excluded and she was started on antituberculous agents. In the absence of systemic, specific complaints or history of exposition, histopathology and culture of MTB remain a key step for the diagnosis.\n                  <\/jats:p>","DOI":"10.1136\/bcr-2020-238795","type":"journal-article","created":{"date-parts":[[2021,2,17]],"date-time":"2021-02-17T10:56:24Z","timestamp":1613559384000},"page":"e238795","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Thyroid tuberculosis: an unexpected diagnosis"],"prefix":"10.1136","volume":"14","author":[{"given":"Alexandra Novais","family":"Ara\u00fajo","sequence":"first","affiliation":[{"name":"Servi\u00e7o de Endocrinologia, Centro Hospitalar Universit\u00e1rio Lisboa Norte EPE, Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00e2nia","family":"Matos","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Endocrinologia, Centro Hospitalar Universit\u00e1rio Lisboa Norte EPE, Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o","family":"Boavida","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Anatomia Patol\u00f3gica, Centro Hospitalar Universit\u00e1rio Lisboa Norte EPE, Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Jo\u00e3o Guerreiro Martins","family":"Bugalho","sequence":"additional","affiliation":[{"name":"Servi\u00e7o de Endocrinologia, Centro Hospitalar Universit\u00e1rio Lisboa Norte EPE, Lisboa, Portugal"},{"name":"Faculdade de Medicina de Lisboa, Lisboa, Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,2,17]]},"reference":[{"key":"2025082708560203000_14.2.e238795.1","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/S0025-7125(16)30188-2","article-title":"The history of tuberculosis as a global epidemic","volume":"77","author":"Bates","year":"1993","journal-title":"Med Clin North Am"},{"key":"2025082708560203000_14.2.e238795.2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0028-1085700"},{"key":"2025082708560203000_14.2.e238795.3","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1089\/thy.2009.0189","article-title":"Histopathologic diagnosis of thyroid tuberculosis","volume":"19","author":"Ozekinci","year":"2009","journal-title":"Thyroid"},{"key":"2025082708560203000_14.2.e238795.4","doi-asserted-by":"crossref","DOI":"10.1093\/omcr\/omx022","article-title":"Incidental finding of a primary thyroid tuberculosis","volume":"2017","author":"Ortiz-Flores","year":"2017","journal-title":"Oxf Med Case Reports"},{"key":"2025082708560203000_14.2.e238795.5","doi-asserted-by":"publisher","DOI":"10.1016\/S2221-1691(12)60240-8"},{"key":"2025082708560203000_14.2.e238795.6","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-005-0139-1"},{"key":"2025082708560203000_14.2.e238795.7","article-title":"Thyroid tuberculosis","volume":"40","author":"Simkus","year":"2004","journal-title":"Medicina"},{"key":"2025082708560203000_14.2.e238795.8","doi-asserted-by":"crossref","first-page":"330","DOI":"10.14310\/horm.2002.1215","article-title":"Primary tuberculosis of the thyroid gland","volume":"7","author":"Zendah","year":"2008","journal-title":"Hormones"},{"key":"2025082708560203000_14.2.e238795.9","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-202792"},{"key":"2025082708560203000_14.2.e238795.10","unstructured":"Kesireddy M , Lasrado S . Cancer, thyroid lymphoma. Treasure Island, FL: StatPearls Publishing StatPearls Publishing LLC, 2019."},{"key":"2025082708560203000_14.2.e238795.11","doi-asserted-by":"crossref","unstructured":"Ali SZ , Cibas ES . The Bethesda system for reporting thyroid cytopathology: definitions, criteria, and explanatory notes. Springer Internacional Publishing Imprint, 2018.","DOI":"10.1007\/978-3-319-60570-8"},{"key":"2025082708560203000_14.2.e238795.12","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1089\/thy.2006.16.1175","article-title":"Thyroid sarcoidosis as a unique localization","volume":"16","author":"Cabibi","year":"2006","journal-title":"Thyroid"},{"key":"2025082708560203000_14.2.e238795.13","unstructured":"World Health Organization . Global tuberculosis report 2018. 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