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After being discharged with reassurance, he re-presented with worsening pain on symptom day 25. Subsequent abdominal ultrasound suggested portal vein thrombosis. CT of the abdomen confirmed portal and mid-superior mesenteric vein thromboses. Concurrent CT of the chest suggested COVID-19 infection. While reverse transcription PCR was negative, subsequent antibody serology was positive. Thrombophilia screen excluded inherited and acquired thrombophilia. Having been commenced on apixaban 5\u2009mg two times per day, he is currently asymptomatic. This is the first case of COVID-19-related portomesenteric thrombosis described in the UK. A recent meta-analysis suggests 9.2% of COVID-19 cases develop abdominal pain. Threshold for performing abdominal imaging must be lower to avoid this reversible complication.<\/jats:p>","DOI":"10.1136\/bcr-2020-238906","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T18:18:21Z","timestamp":1608661101000},"page":"e238906","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":17,"title":["Spontaneous portomesenteric thrombosis in a non-cirrhotic patient with SARS-CoV-2 infection"],"prefix":"10.1136","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7301-8250","authenticated-orcid":false,"given":"Kushala WM","family":"Abeysekera","sequence":"first","affiliation":[{"name":"Department of Liver Medicine, Bristol Royal Infirmary, Bristol, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hedvig","family":"Karteszi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Bristol Royal Infirmary, Bristol, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Clark","sequence":"additional","affiliation":[{"name":"Bristol Haematology and Oncology Centre, Bristol Royal Infirmary, Bristol, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fiona H","family":"Gordon","sequence":"additional","affiliation":[{"name":"Department of Liver Medicine, Bristol Royal Infirmary, Bristol, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2020,12,22]]},"reference":[{"key":"2025082804235867000_13.12.e238906.1","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","article-title":"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China","volume":"395","author":"Huang","year":"2020","journal-title":"The Lancet"},{"key":"2025082804235867000_13.12.e238906.2","doi-asserted-by":"publisher","DOI":"10.1111\/jth.14768"},{"key":"2025082804235867000_13.12.e238906.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.04.031"},{"key":"2025082804235867000_13.12.e238906.4","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1111\/jth.14830","article-title":"Prevalence of venous thromboembolism in patients with severe novel coronavirus pneumonia","volume":"18","author":"Cui","year":"2020","journal-title":"J Thromb Haemost"},{"key":"2025082804235867000_13.12.e238906.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2020.04.013"},{"key":"2025082804235867000_13.12.e238906.6","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.thromres.2020.06.019","article-title":"Portal vein thrombosis in a patient with COVID-19","volume":"194","author":"Franco-Moreno","year":"2020","journal-title":"Thromb Res"},{"key":"2025082804235867000_13.12.e238906.7","doi-asserted-by":"crossref","unstructured":"de Barry O , Mekki A , Diffre C , et al . 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