{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:03:37Z","timestamp":1756339417021,"version":"3.44.0"},"reference-count":19,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,2,15]]},"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:p>A 64-year-old woman referred to Gynaecological Oncology secondary to the finding of pelvic mass and ascites. Imaging showed multiple pelvic masses, with the largest mass measuring 20 cm in diameter, as well as bilateral pleural effusions and abdominal ascites, suspicious for ovarian carcinoma. Laboratory findings included elevated cancer antigen 125 (CA-125) of 2124 units\/mL. The patient underwent an exploratory laparotomy, total abdominal hysterectomy and bilateral salpingo-oophorectomy for pathological evaluation. Postoperatively, the patient had resolution of ascites and pleural effusion. Surgical pathology revealed a 26 cm right ovarian fibroma, confirming the diagnosis of Meigs syndrome. Despite the high suspicion for ovarian carcinoma in patients presenting with elevated CA-125 level, pelvic mass, ascites and pleural effusion, the diagnosis of Meigs syndrome cannot be excluded without pathological evaluation of mass.<\/jats:p>","DOI":"10.1136\/bcr-2020-238931","type":"journal-article","created":{"date-parts":[[2021,3,2]],"date-time":"2021-03-02T10:56:41Z","timestamp":1614682601000},"page":"e238931","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Meigs syndrome presenting with severely elevated CA-125 level"],"prefix":"10.1136","volume":"14","author":[{"given":"Alicia","family":"Palmieri","sequence":"first","affiliation":[{"name":"Obstetrics & Gynecology, Jersey Shore University Medical Center, Neptune City, New Jersey, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3182-0808","authenticated-orcid":false,"given":"Karim","family":"ElSahwi","sequence":"additional","affiliation":[{"name":"Gynecology Oncology, Jersey Shore University Medical Center, Neptune City, New Jersey, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Verda","family":"Hicks","sequence":"additional","affiliation":[{"name":"Gynecology Oncology, Jersey Shore University Medical Center, Neptune City, New Jersey, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,3,2]]},"reference":[{"key":"2025082702480056000_14.3.e238931.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2008.03.053"},{"key":"2025082702480056000_14.3.e238931.2","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/S0002-9378(37)80015-0","article-title":"Fibroma of the ovary with ascites and hydrothorax: with a report of seven cases","volume":"33","author":"Meigs","year":"1938","journal-title":"Am J Obstet Gynecol"},{"key":"2025082702480056000_14.3.e238931.3","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.2004.018077"},{"key":"2025082702480056000_14.3.e238931.4","first-page":"686","article-title":"Ovarian tumors. 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