{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:28:05Z","timestamp":1761845285510,"version":"3.44.0"},"reference-count":12,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,12,16]]},"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>Posterior reversible encephalopathy syndrome (PRES) is a neurological syndrome manifesting with acute focal signs, and concomitant neuroimaging findings of vasogenic oedema. It affects the parieto-occipital regions in a vast majority of cases, although atypical variants have been described comprising the brainstem, basal ganglia or spinal cord. We report the case of a 41-year-old woman, admitted for persistent headache and inferior altitudinal field defect in the right eye. She presented with severe, non-medicated, hypertension. Brain MRI showed findings compatible with atypical PRES, involving the brainstem and optic pathways. With antihypertensive therapy the headache remitted, although visual field remained and was interpreted in the context of a vascular aetiology\u2014non-arteritic anterior ischaemic optic neuropathy. MRI was repeated 3\u2009weeks later and showed almost complete reversal of the previous changes.<\/jats:p>","DOI":"10.1136\/bcr-2020-239130","type":"journal-article","created":{"date-parts":[[2021,1,12]],"date-time":"2021-01-12T15:40:59Z","timestamp":1610466059000},"page":"e239130","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Optic pathways and brainstem involvement in posterior reversible encephalopathy syndrome"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5989-9792","authenticated-orcid":false,"given":"Sofia Grenho","family":"Rodrigues","sequence":"first","affiliation":[{"name":"Neurology Department, Hospital da Luz Lisboa, Lisboa, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paulo","family":"Saraiva","sequence":"additional","affiliation":[{"name":"Neuroradiology Department, Hospital da Luz Lisboa, Lisboa, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In\u00eas Br\u00e1s","family":"Marques","sequence":"additional","affiliation":[{"name":"Neurology Department, Hospital da Luz Lisboa, Lisboa, Lisboa, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,1,11]]},"reference":[{"key":"2025082711415363000_14.1.e239130.1","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1016\/j.jns.2019.07.018","article-title":"Posterior reversible encephalopathy syndrome: a review with emphasis on neuroimaging characteristics","volume":"404","author":"Tetsuka","year":"2019","journal-title":"J Neurol Sci"},{"key":"2025082711415363000_14.1.e239130.2","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A0549"},{"key":"2025082711415363000_14.1.e239130.3","doi-asserted-by":"publisher","DOI":"10.1177\/0885066610393634"},{"key":"2025082711415363000_14.1.e239130.4","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.clinimag.2017.08.008","article-title":"The imaging spectrum of posterior reversible encephalopathy syndrome: a pictorial review","volume":"47","author":"Brady","year":"2018","journal-title":"Clin Imaging"},{"key":"2025082711415363000_14.1.e239130.5","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2009.0590"},{"key":"2025082711415363000_14.1.e239130.6","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.07.2024"},{"key":"2025082711415363000_14.1.e239130.7","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.radcr.2019.02.009","article-title":"Posterior reversible encephalopathy syndrome with isolated infratentorial involvement: a case report","volume":"14","author":"Samara","year":"2019","journal-title":"Radiol Case Rep"},{"key":"2025082711415363000_14.1.e239130.8","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)00111-8"},{"key":"2025082711415363000_14.1.e239130.9","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.12.9677"},{"key":"2025082711415363000_14.1.e239130.10","doi-asserted-by":"crossref","first-page":"1608","DOI":"10.1007\/s00415-016-8377-8","article-title":"Posterior reversible encephalopathy syndrome","volume":"264","author":"Fischer","year":"2017","journal-title":"J Neurol"},{"key":"2025082711415363000_14.1.e239130.11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2012.02.023"},{"key":"2025082711415363000_14.1.e239130.12","doi-asserted-by":"publisher","DOI":"10.1097\/WCO.0000000000000640"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-239130","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T18:42:00Z","timestamp":1756320120000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-239130"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":12,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2021,1,11]]},"published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1136\/bcr-2020-239130"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-239130","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2021,1]]}}}