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The disease can affect any organ in the body but mainly presents as bilateral hilar lymphadenopathy, pulmonary infiltrates, cutaneous lesions, ocular manifestations and arthropathy. Lofgren\u2019s syndrome is an uncommon initial presentation of sarcoidosis which is recognised by the classical triad of acute arthritis, erythema nodosum and bilateral hilar lymphadenopathy. We describe a newly diagnosed case of sarcoidosis who presented as Lofgren\u2019s syndrome. Acute sarcoid arthritis should be kept as one of the differential diagnoses for patients presenting with acute arthritis and skin lesions; and chest X-ray should be considered to rule out bilateral hilar lymphadenopathy in these patients. Early suspicion and identification of classical clinical features are essential to establish early diagnosis.<\/jats:p>","DOI":"10.1136\/bcr-2020-239239","type":"journal-article","created":{"date-parts":[[2021,6,7]],"date-time":"2021-06-07T12:37:55Z","timestamp":1623069475000},"page":"e239239","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Acute arthritis, skin rash and Lofgren\u2019s syndrome"],"prefix":"10.1136","volume":"14","author":[{"given":"Ajay","family":"Chauhan","sequence":"first","affiliation":[{"name":"Internal Medicine, Dr Rajinder Prasad Government Medical College, Kangra, Himachal Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6426-0309","authenticated-orcid":false,"given":"Aditya","family":"Jandial","sequence":"additional","affiliation":[{"name":"Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5754-0946","authenticated-orcid":false,"given":"Kundan","family":"Mishra","sequence":"additional","affiliation":[{"name":"Internal Medicine, Army Hospital Research and Referral, New Delhi, Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajeev","family":"Sandal","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy and Oncology, IGMC, Shimla, Himachal Pradesh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,6,7]]},"reference":[{"key":"2025082707241230000_14.6.e239239.1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra071714"},{"key":"2025082707241230000_14.6.e239239.2","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1002\/acr.22737","article-title":"Clinical characteristics of sarcoid arthropathy: a population-based study","volume":"68","author":"Ungprasert","year":"2016","journal-title":"Arthritis Care Res"},{"key":"2025082707241230000_14.6.e239239.3","doi-asserted-by":"publisher","DOI":"10.1136\/ard.61.6.499"},{"key":"2025082707241230000_14.6.e239239.4","doi-asserted-by":"crossref","first-page":"1728","DOI":"10.1111\/1756-185X.13349","article-title":"Arthritis in sarcoidosis: a multicentric study from India","volume":"21","author":"Agarwal","year":"2018","journal-title":"Int J Rheum Dis"},{"key":"2025082707241230000_14.6.e239239.5","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.3390\/jcm9041081","article-title":"Sarcoidosis: causes, diagnosis, clinical features, and treatments","volume":"9","author":"Jain","year":"2020","journal-title":"J Clin Med"},{"key":"2025082707241230000_14.6.e239239.6","first-page":"325","article-title":"Sarcoidosis: a review for the internist","volume":"13","author":"Bargagli","year":"2018","journal-title":"Intern Emerg Med"},{"key":"2025082707241230000_14.6.e239239.7","doi-asserted-by":"crossref","DOI":"10.7326\/0003-4819-156-9-201205010-01005","article-title":"Sarcoidosis","volume":"156","author":"O'Regan","year":"2012","journal-title":"Ann Intern Med"},{"key":"2025082707241230000_14.6.e239239.8","unstructured":"Brown F , Modi P , Tanner LS . Lofgren syndrome. StatPearls. 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