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We report a case of a 45-year-old woman with the history of sputum positive pulmonary TB, presenting with seizures and eventually found to have developed disseminated infection involving multiple organs, including the aorta. The patient was started on WHO-recommended anti-tubercular treatment but ended up requiring surgical intervention for the aneurysm. Although the main modality of treatment is the use of proper and adequate medical therapy, vascular dissemination in the form of mycotic aneurysm is difficult to be dealt singlehandedly due to their irreversible and multifactorial nature, with infection being the leading cause and their tendency to progress despite the primary infection being treated.<\/jats:p>","DOI":"10.1136\/bcr-2020-239309","type":"journal-article","created":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T11:07:03Z","timestamp":1613646423000},"page":"e239309","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Tuberculous mycotic aneurysm of aortic arch: a case report emphasising on multidisciplinary management approach"],"prefix":"10.1136","volume":"14","author":[{"given":"Dhivya","family":"Velu","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, UAB Huntvsille Regional Medical Campus, Huntsville, Alabama, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farrah","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, UAB Huntvsille Regional Medical Campus, Huntsville, Alabama, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Hassoun","sequence":"additional","affiliation":[{"name":"Department of Infectious disease, Alabama Infectious Disease Center\/Huntsville Hospital Health System, Huntsville, Alabama, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,2,18]]},"reference":[{"key":"2025082801220287000_14.2.e239309.1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.1263.522"},{"key":"2025082801220287000_14.2.e239309.2","first-page":"307","article-title":"Ueber Venentuberkel und ihre Beziehungen Zur tubercul\u00f6sen Blutinfection","volume":"88","author":"Weigert","year":"1882","journal-title":"Archiv f\u00fcr Pathologische Anatomie und Physiologie und f\u00fcr Klinische Medicin"},{"key":"2025082801220287000_14.2.e239309.3","unstructured":"Who.int . 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