{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:03:08Z","timestamp":1756425788612,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,4,6]]},"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:p>The authors present a case of a 42-year-old previously healthy man who presented in sepsis, with right lateral gaze palsy. He was found to have bilateral cavernous sinus thrombosis (CST) and bilateral internal jugular thrombosis in the setting of <jats:italic>Staphylococcus aureus<\/jats:italic> bacteraemia. The patient was successfully treated and recovered from his illness after a protracted stay in the medical intensive care unit. We go over the treatment course and follow-up of this patient and discuss the need to have a high degree of clinical suspicion for CST and suppurative thrombophlebitis of the internal jugular veins. We also discuss the possible role of the Panton-Valentine leukocidin in causing thrombotic complications of <jats:italic>S. aureus<\/jats:italic> bacteraemia.<\/jats:p>","DOI":"10.1136\/bcr-2020-239359","type":"journal-article","created":{"date-parts":[[2021,4,22]],"date-time":"2021-04-22T11:46:54Z","timestamp":1619092014000},"page":"e239359","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Intracranial thrombosis associated with MSSA bacteraemia in the setting of influenza A"],"prefix":"10.1136","volume":"14","author":[{"given":"Sairam","family":"Raghavan","sequence":"first","affiliation":[{"name":"Internal Medicine, John H Stroger Hospital of Cook County, Chicago, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0197-8970","authenticated-orcid":false,"given":"Sriram","family":"Gonakoti","sequence":"additional","affiliation":[{"name":"Internal Medicine, John H Stroger Hospital of Cook County, Chicago, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis","family":"Parra-Rodriguez","sequence":"additional","affiliation":[{"name":"Internal Medicine, John H Stroger Hospital of Cook County, Chicago, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,4,22]]},"reference":[{"key":"2025082801080696000_14.4.e239359.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2015.09.037"},{"key":"2025082801080696000_14.4.e239359.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2012.06.013"},{"key":"2025082801080696000_14.4.e239359.3","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1017\/cjn.2016.438","article-title":"Bilateral cavernous sinus thrombosis in Lemierre's syndrome","volume":"44","author":"Budhram","year":"2017","journal-title":"Can J Neurol Sci"},{"key":"2025082801080696000_14.4.e239359.4","doi-asserted-by":"crossref","first-page":"483","DOI":"10.5692\/clinicalneurol.cn-000676","article-title":"[A case with both infectious cavernous sinus thrombosis and Lemierre syndrome due to intraoral resident flora]","volume":"55","author":"Nishida","year":"2015","journal-title":"Rinsho Shinkeigaku"},{"key":"2025082801080696000_14.4.e239359.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2012.02.075"},{"key":"2025082801080696000_14.4.e239359.6","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.47281-0"},{"key":"2025082801080696000_14.4.e239359.7","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1097\/INF.0000000000001667","article-title":"Panton-Valentine leukocidin producing Staphylococcus aureus facial pyomyositis causing partial cavernous sinus thrombosis","volume":"36","author":"Green","year":"2017","journal-title":"Pediatr Infect Dis J"},{"key":"2025082801080696000_14.4.e239359.8","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1016\/j.joms.2014.10.004","article-title":"Panton-Valentine leukocidin positive staphylococcal aureus infections of the head and neck: case series and brief review of literature","volume":"73","author":"Hanratty","year":"2015","journal-title":"J Oral Maxillofac Surg"},{"key":"2025082801080696000_14.4.e239359.9","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1177\/0003489419832624","article-title":"Orbital complications of rhinosinusitis in the adult population: analysis of cases presenting to a tertiary medical center over a 13-year period","volume":"128","author":"El Mograbi","year":"2019","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"2025082801080696000_14.4.e239359.10","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12398"},{"key":"2025082801080696000_14.4.e239359.11","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.9743"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-239359","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T08:08:19Z","timestamp":1756368499000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-239359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":11,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,4,22]]},"published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1136\/bcr-2020-239359"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-239359","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2021,4]]}}}