{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:03:47Z","timestamp":1756425827944,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,5,5]]},"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:p>We present two French cases of amyloid-associated (AA) amyloidosis secondary to chronic infections. Patient 1, a 51-year-old heroin addict, was hospitalised for chest pain and anasarca. During hospitalisation, a nephrotic syndrome with an inflammatory condition was discovered along with a chronic skin ulcer on his arm. Salivary gland and kidney biopsies confirmed the diagnosis of AA amyloidosis. Renal function quickly declined and haemodialysis was initiated 6 months later. Patient 2, a 55-year-old woman, was hospitalised for obstructive pyelonephritis secondary to coraliform lithiasis. Renal insufficiency with an impure nephrotic syndrome was found. After nephrectomy due to chronic pyelonephritis and an atrophic cortex on the abdominal scan, the histology revealed AA amyloidosis. Despite treatment with ACE inhibitors and control of inflammation, the nephrotic syndrome persisted with rapid decline of the kidney function.<\/jats:p>","DOI":"10.1136\/bcr-2020-239411","type":"journal-article","created":{"date-parts":[[2021,6,7]],"date-time":"2021-06-07T12:37:05Z","timestamp":1623069425000},"page":"e239411","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Two cases of secondary AA amyloidosis involving the skin and chronic kidney infection with a nephrotic syndrome in a high-income country"],"prefix":"10.1136","volume":"14","author":[{"given":"Florian","family":"Garo","sequence":"first","affiliation":[{"name":"Nephrology Dialysis Apheresis, Hopital Universitaire de Nimes, CHU Caremeau, Nimes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juliette","family":"Chatelain","sequence":"additional","affiliation":[{"name":"Nephrology Dialysis Apheresis, Hopital Universitaire de Nimes, CHU Caremeau, Nimes, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cedric","family":"Aglae","sequence":"additional","affiliation":[{"name":"Nephrology Dialysis Apheresis, Hopital Universitaire de Nimes, CHU Caremeau, Nimes, France"},{"name":"Faculty of Medicine, University of Montpellier, Montpellier, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3127-1415","authenticated-orcid":false,"given":"Olivier","family":"Moranne","sequence":"additional","affiliation":[{"name":"Nephrology Dialysis Apheresis, Hopital Universitaire de Nimes, CHU Caremeau, Nimes, France"},{"name":"Faculty of Medicine, University of Montpellier, Montpellier, France"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,6,7]]},"reference":[{"key":"2025082802183850000_14.6.e239411.1","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.rdc.2018.06.004","article-title":"Secondary, AA, amyloidosis","volume":"44","author":"Papa","year":"2018","journal-title":"Rheum Dis Clin North Am"},{"key":"2025082802183850000_14.6.e239411.2","first-page":"258","article-title":"N\u00e9phrologie & Th\u00e9rapeutique","volume":"13","author":"Stojanovic","year":"2017","journal-title":"Juin"},{"key":"2025082802183850000_14.6.e239411.3","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1016\/j.rce.2012.09.001","article-title":"Caracter\u00edsticas cl\u00ednicas de los pacientes con amiloidosis sist\u00e9micas en el periodo 2000 - 2010","volume":"213","author":"Real de As\u00faa","year":"2013","journal-title":"Revista Cl\u00ednica Espa\u00f1ola"},{"key":"2025082802183850000_14.6.e239411.4","doi-asserted-by":"crossref","first-page":"369","DOI":"10.2147\/CLEP.S39981","article-title":"Systemic AA amyloidosis: epidemiology, diagnosis, and management","volume":"6","author":"Real de As\u00faa","year":"2014","journal-title":"Clin Epidemiol"},{"key":"2025082802183850000_14.6.e239411.5","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1080\/13506129.2017.1289917","article-title":"Prognostication of survival and progression to dialysis in AA amyloidosis","volume":"24","author":"Palladini","year":"2017","journal-title":"Amyloid"},{"key":"2025082802183850000_14.6.e239411.6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa070265"},{"key":"2025082802183850000_14.6.e239411.7","doi-asserted-by":"publisher","DOI":"10.1002\/art.23579"},{"key":"2025082802183850000_14.6.e239411.8","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcl092"},{"key":"2025082802183850000_14.6.e239411.9","doi-asserted-by":"publisher","DOI":"10.3109\/13506129.2011.613962"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-239411","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T09:18:49Z","timestamp":1756372729000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-239411"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":9,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,6,7]]},"published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1136\/bcr-2020-239411"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-239411","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2021,6]]}}}