{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T23:39:22Z","timestamp":1781307562988,"version":"3.54.1"},"reference-count":11,"publisher":"BMJ","issue":"1","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2020,12,11]]},"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:p>An 85-year-old man was referred to endocrinology following the discovery of an incidental pituitary mass on cranial imaging which was thought to be a non-functioning adenoma during an admission with headaches, lethargy, confusion and hyponatraemia. He had a history of H\u00fcrthle cell carcinoma of the thyroid treated with total thyroidectomy, ablative radioiodine therapy and thyroxine replacement. Subsequently, he developed metastatic spread to the neck, lungs and skeleton. About 9 months later, the patient had deterioration of vision. MRI showed a rapidly expanding pituitary mass with compression of the optic chiasm. Biochemical investigations confirmed hypocortisolism and hypogonadism. The patient underwent trans-sphenoidal resection of the pituitary mass followed by external beam radiotherapy to the pituitary bed. Histopathology confirmed a metastatic deposit of H\u00fcrthle cell carcinoma, which is a rare and aggressive variant of follicular thyroid carcinoma.<\/jats:p>","DOI":"10.1136\/bcr-2020-239456","type":"journal-article","created":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T12:31:07Z","timestamp":1610973067000},"page":"e239456","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Pituitary metastases of H\u00fcrthle cell carcinoma of the thyroid"],"prefix":"10.1136","volume":"14","author":[{"given":"Nosakhare Paul","family":"Ilerhunmwuwa","sequence":"first","affiliation":[{"name":"Diabetes and Endocrinology, Queen's Medical Centre Nottingham University Hospital NHS Trust, Nottingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Goldspring","sequence":"additional","affiliation":[{"name":"Pathology, Queen's Medical Centre Nottingham University Hospital NHS Trust, Nottingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon","family":"Page","sequence":"additional","affiliation":[{"name":"Diabetes and Endocrinology, Queen's Medical Centre Nottingham University Hospital NHS Trust, Nottingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravikanth","family":"Gouni","sequence":"additional","affiliation":[{"name":"Diabetes and Endocrinology, Queen's Medical Centre Nottingham University Hospital NHS Trust, Nottingham, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,1,18]]},"reference":[{"key":"2025082802363122000_14.1.e239456.1","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1007\/s12020-012-9806-9","article-title":"Pituitary metastasis of thyroid cancer","volume":"43","author":"Barbaro","year":"2013","journal-title":"Endocrine"},{"key":"2025082802363122000_14.1.e239456.2","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-2-27"},{"key":"2025082802363122000_14.1.e239456.3","doi-asserted-by":"crossref","first-page":"896","DOI":"10.12659\/AJCR.909523","article-title":"Pituitary metastasis of thyroid carcinoma: a case report","volume":"19","author":"Souza Mota","year":"2018","journal-title":"Am J Case Rep"},{"key":"2025082802363122000_14.1.e239456.4","doi-asserted-by":"crossref","first-page":"261","DOI":"10.5114\/fn.2013.37711","article-title":"Pituitary metastases from the oncocytic variant of follicular thyroid carcinoma: a case report and diagnostic dilemmas","volume":"51","author":"Matyja","year":"2013","journal-title":"Folia Neuropathol"},{"key":"2025082802363122000_14.1.e239456.5","unstructured":"Nikiforov YE , Biddinger PW , Thompson LDR . 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