{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T12:17:38Z","timestamp":1777897058555,"version":"3.51.4"},"reference-count":16,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,1,23]]},"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:p>Iatrogenic iron overload, which is not uncommon in patients undergoing long-term haemodialysis, arises from a combination of multiple red cell transfusions and parenteral iron infusions that are administered to maintain a haemoglobin concentration of approximately 10 g\/dL. Although iron overload due to genetic haemochromatosis is conventionally managed by phlebotomy, patients with haemoglobinopathies and chronic transfusion-induced iron overload are treated with iron-chelation therapy. However, the management of iron overload in our patient who presented with hepatic dysfunction and immunosuppressive drug-induced mild anaemia in the post-renal transplant setting posed unique challenges. We report on the decision-making process used in such a case that led to a successful clinical resolution of hepatic iron overload through the combined use of phlebotomy and erythropoiesis stimulating agents, while avoiding use of iron-chelating agents that could potentially compromise both hepatic and renal function.<\/jats:p>","DOI":"10.1136\/bcr-2020-239568","type":"journal-article","created":{"date-parts":[[2021,2,7]],"date-time":"2021-02-07T10:05:45Z","timestamp":1612692345000},"page":"e239568","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical conundrum: managing iron overload after renal transplantation"],"prefix":"10.1136","volume":"14","author":[{"given":"Binayak","family":"Upadhyay","sequence":"first","affiliation":[{"name":"Internal Medicine, AMITA Health Saint Francis Hospital Evanston, Evanston, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven 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