{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T23:40:32Z","timestamp":1788306032566,"version":"build-2803163510"},"reference-count":10,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,2,2]]},"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:p>The obstructed hemivagina and ipsilateral renal agenesis (OHVIRA) syndrome, a rare Mullerian duct anomaly, is a triad of uterine anomalies with ipsilateral renal agenesis and obstructed hemivagina. The aetiopathogenesis of this developmental anomaly is debatable, with several theories being postulated to explain its occurrence. We report two cases of this rare syndrome which were detected on imaging done for unrelated reasons. Case 1 is a 24-year-old woman who presented with primary infertility. After an incidental detection of the syndrome and ruling out a male factor, she has been planned for excision of the vaginal septum. Case 2 is a 47-year-old woman with OHVIRA detected during the evaluation of urolithiasis and is asymptomatic for the syndrome. The OHVIRA syndrome can be asymptomatic or may present as haematocolpos, pelvic pain and infertility which requires surgical intervention, after which successful pregnancies have been reported.<\/jats:p>","DOI":"10.1136\/bcr-2020-239625","type":"journal-article","created":{"date-parts":[[2021,2,10]],"date-time":"2021-02-10T11:45:05Z","timestamp":1612957505000},"page":"e239625","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Female counterpart of the Zinner syndrome in men: decoding the \u2018OHVIRA\u2019 syndrome"],"prefix":"10.1136","volume":"14","author":[{"given":"Vikas Kumar","family":"Panwar","sequence":"first","affiliation":[{"name":"Urology, All India Institute of Medical Sciences, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tushar Aditya","family":"Narain","sequence":"additional","affiliation":[{"name":"Urology, All India Institute of Medical Sciences, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankur","family":"Mittal","sequence":"additional","affiliation":[{"name":"Urology, All India Institute of Medical Sciences, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harkirat Singh","family":"Talwar","sequence":"additional","affiliation":[{"name":"Urology, All India Institute of Medical Sciences, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,2,10]]},"reference":[{"key":"2025082800481302000_14.2.e239625.1","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4103\/0974-1208.97811","article-title":"OHVIRA: uterus didelphys, blind hemivagina and ipsilateral renal agenesis: advantage MRI","volume":"5","author":"Bajaj","year":"2012","journal-title":"J Hum Reprod Sci"},{"key":"2025082800481302000_14.2.e239625.2","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1080\/15476278.2016.1145317","article-title":"New theory of uterovaginal embryogenesis","volume":"12","author":"Makiyan","year":"2016","journal-title":"Organogenesis"},{"key":"2025082800481302000_14.2.e239625.3","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0015-0282(16)35882-4","article-title":"Fertility and unification of double uterus","volume":"17","author":"Strassmann","year":"1966","journal-title":"Fertil Steril"},{"key":"2025082800481302000_14.2.e239625.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.fertnstert.2007.01.173"},{"key":"2025082800481302000_14.2.e239625.5","unstructured":"Sadler TW . Langman\u2019s Medical Embryology.\u201d IX-th edn Baltimore:Lippincott Williams&Wilkins, 2000. Available: https:\/\/archive.org\/stream\/LangmansMedicalEmbryology#page\/n342\/mode\/1up"},{"key":"2025082800481302000_14.2.e239625.6","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/"},{"key":"2025082800481302000_14.2.e239625.7","doi-asserted-by":"crossref","first-page":"243","DOI":"10.4103\/0971-3026.120283","article-title":"Herlyn-Werner-Wunderlich syndrome presenting with infertility: role of MRI in diagnosis","volume":"23","author":"Ahmad","year":"2013","journal-title":"Indian J Radiol Imaging"},{"key":"2025082800481302000_14.2.e239625.8","doi-asserted-by":"crossref","first-page":"375","DOI":"10.4103\/ijri.IJRI_401_17","article-title":"OHVIRA and OSVIRA syndrome","volume":"28","author":"Koticha","year":"2018","journal-title":"Indian J Radiol Imaging"},{"key":"2025082800481302000_14.2.e239625.9","first-page":"QD15","article-title":"Treatment of virgin OHVIRA syndrome with Haematometrocolpos by complete incision of vaginal septum without Hymenotomy","volume":"9","author":"Tug","year":"2015","journal-title":"J Clin Diagn Res"},{"key":"2025082800481302000_14.2.e239625.10","first-page":"6","article-title":"Imaging diagnosis of Herlyn-Werner-Wunderlich Syndrome- an extremely rare urogenital anomaly","volume":"9","author":"Mehra","year":"2015","journal-title":"J Clin Diagn Res"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-239625","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T07:48:20Z","timestamp":1756367300000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-239625"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":10,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,2,10]]},"published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1136\/bcr-2020-239625"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-239625","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2]]}}}