{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,24]],"date-time":"2025-12-24T12:41:26Z","timestamp":1766580086308,"version":"3.44.0"},"reference-count":20,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,1,28]]},"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:p>Leiomyosarcomas are soft tissue tumours that rarely occur in the larynx. This case report describes the presentation and management of a 77-year-old man referred to the otolaryngology clinic with hoarseness who was found to have a large supraglottic leiomyosarcoma after panendoscopy and biopsies. He subsequently underwent laryngectomy for treatment of this tumour but, unexpectedly, the histological analysis of the laryngectomy specimen revealed a second primary tumour in the larynx\u2014a squamous cell carcinoma (SCC). The patient had further treatment with neck radiotherapy. Three years after treatment, there are no signs of recurrence of either tumour. This case report discusses the very few similar cases of leiomyosarcoma coexisting with SCC in the larynx, collating the evidence surrounding the treatment of this rare presentation.<\/jats:p>","DOI":"10.1136\/bcr-2020-239797","type":"journal-article","created":{"date-parts":[[2021,2,18]],"date-time":"2021-02-18T11:04:04Z","timestamp":1613646244000},"page":"e239797","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Simultaneous double laryngeal tumours: a diagnostic and therapeutic challenge"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1911-0440","authenticated-orcid":false,"given":"Fergus","family":"Cooper","sequence":"first","affiliation":[{"name":"Otolaryngology, Aberdeen Royal Infirmary, Aberdeen, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Moleron","sequence":"additional","affiliation":[{"name":"Oncology, Aberdeen Royal Infirmary, Aberdeen, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Chapman","sequence":"additional","affiliation":[{"name":"Pathology, Aberdeen Royal Infirmary, Aberdeen, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6240-5957","authenticated-orcid":false,"given":"Muhammad","family":"Shakeel","sequence":"additional","affiliation":[{"name":"Otolaryngology, Aberdeen Royal Infirmary, Aberdeen, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,2,18]]},"reference":[{"key":"2025082712013107000_14.2.e239797.1","unstructured":"Barnes L , Eveson JW , Reichart P . 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