{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:07:17Z","timestamp":1756339637652,"version":"3.44.0"},"reference-count":7,"publisher":"BMJ","issue":"5","funder":[{"DOI":"10.13039\/501100005809","name":"Hyderabad Eye Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,4,27]]},"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:p>We report an unusual case of acquired oculomotor synkinesis as a sequela of cavernous sinus thrombosis in a child. A 4-year-old male child presented to our emergency services with sudden onset periorbital swelling with complete ptosis of the left upper eyelid. This was preceded by a febrile episode and a furuncle at the tip of the nose. Computerised axial tomography of the orbit revealed orbital cellulitis in the left eye. The child was started on systemic antibiotics followed by a short course of systemic steroids. MRI of the brain with contrast revealed left cavernous sinus and superior ophthalmic vein thrombosis. Following administration of systemic anticoagulants and antibiotics, the ocular motility and ptosis improved remarkably. However, 6\u2009months post-treatment, the child developed signs of aberrant regeneration of the third cranial nerve (oculomotor synkinesis).<\/jats:p>","DOI":"10.1136\/bcr-2020-239819","type":"journal-article","created":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T13:11:15Z","timestamp":1620911475000},"page":"e239819","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Oculomotor synkinesis: an uncommon sequela of paediatric cavernous sinus thrombosis"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4530-1707","authenticated-orcid":false,"given":"Sakshi","family":"Lalwani","sequence":"first","affiliation":[{"name":"Paediatric Ophthalmology, Strabismus and Neuro-ophthalmology, Jasti V Ramanamma Children's Eye care Center, Child Sight Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5789-2300","authenticated-orcid":false,"given":"Ramesh","family":"Kekunnaya","sequence":"additional","affiliation":[{"name":"Paediatric Ophthalmology, Strabismus and Neuro-ophthalmology, Jasti V Ramanamma Children's Eye care Center, Child Sight Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jenil","family":"Sheth","sequence":"additional","affiliation":[{"name":"Paediatric Ophthalmology, Strabismus and Neuro-ophthalmology, Jasti V Ramanamma Children's Eye care Center, Child Sight Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,5,13]]},"reference":[{"key":"2025082713210327000_14.5.e239819.1","unstructured":"Plewa MC , Tadi P , Gupta M . Cavernous Sinus Thrombosis. [Updated 2021 Feb 3]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing, 2021 Jan."},{"key":"2025082713210327000_14.5.e239819.2","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1212\/WNL.0000000000001886","article-title":"Pediatric cavernous sinus thrombosis: a case series and review of the literature","volume":"85","author":"Smith","year":"2015","journal-title":"Neurology"},{"key":"2025082713210327000_14.5.e239819.3","first-page":"617","article-title":"Tributary venosinus occlusion and septic cavernous sinus thrombosis: CT and Mr findings","volume":"19","author":"Schuknecht","year":"1998","journal-title":"AJNR Am J Neuroradiol"},{"key":"2025082713210327000_14.5.e239819.4","doi-asserted-by":"crossref","DOI":"10.3171\/FOC-07\/11\/E14","article-title":"Aberrant regeneration of the oculomotor nerve: implications for neurosurgeons","volume":"23","author":"Weber","year":"2007","journal-title":"Neurosurg Focus"},{"key":"2025082713210327000_14.5.e239819.5","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.08.1838"},{"key":"2025082713210327000_14.5.e239819.6","doi-asserted-by":"crossref","first-page":"1058","DOI":"10.4103\/ijo.IJO_320_17","article-title":"Contralateral eye surgery with adjustable suture for management of third nerve palsy with aberrant regeneration","volume":"65","author":"Thanh Nguyen","year":"2017","journal-title":"Indian J Ophthalmol"},{"key":"2025082713210327000_14.5.e239819.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)76900-4"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-239819","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T20:21:07Z","timestamp":1756326067000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-239819"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":7,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,5,13]]},"published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1136\/bcr-2020-239819"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-239819","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}