{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T17:29:22Z","timestamp":1761845362479,"version":"3.44.0"},"reference-count":20,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,2,27]]},"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:p>Here, we present three cases of women with interstitial pregnancy who were managed with local instillation of potassium chloride. These women were in their 20s\u201330s and presented in stable condition. Of them, two had a history of previous ectopic pregnancy. Interstitial pregnancy was diagnosed by transvaginal sonography which showed an empty uterine cavity with a gestational sac 1\u2009cm away from the lateral edge of the uterine cavity, with &lt;5\u2009mm myometrium surrounding it in all planes. Two of the three cases failed to respond to methotrexate injection. Due to the presence of high-end ultrasound machine and technical expertise, local instillation of potassium chloride was offered as an alternative to surgical treatment, which is definitive, and all three patients had a successful outcome. One patient returned with pain in the abdomen, which required inpatient monitoring and was later diagnosed with urinary tract infection and was given appropriate antibiotics.<\/jats:p>","DOI":"10.1136\/bcr-2020-239918","type":"journal-article","created":{"date-parts":[[2021,3,23]],"date-time":"2021-03-23T11:57:09Z","timestamp":1616500629000},"page":"e239918","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Successful management of three cases of interstitial pregnancies with local instillation of potassium chloride: avoiding a potential cornuostomy"],"prefix":"10.1136","volume":"14","author":[{"given":"Vineetha","family":"Shetty","sequence":"first","affiliation":[{"name":"Obstetrics and Gynecology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roopa","family":"Padavagodu Shivananda","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akhila","family":"Vasudeva","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyothi","family":"Shetty","sequence":"additional","affiliation":[{"name":"Obstetrics and Gynecology, Kasturba Medical College, Manipal Academy of Higher Education, Manipal, Karnataka, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,3,23]]},"reference":[{"key":"2025082707172999000_14.3.e239918.1","doi-asserted-by":"crossref","first-page":"1271","DOI":"10.1016\/0002-9378(53)90167-7","article-title":"Interstitial pregnancy; a survey of 45 cases","volume":"66","author":"FELMUS","year":"1953","journal-title":"Am J Obstet Gynecol"},{"key":"2025082707172999000_14.3.e239918.2","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1097\/00003081-198012000-00023","article-title":"Anatomy and physiology of the fallopian tube","volume":"23","author":"Eddy","year":"1980","journal-title":"Clin Obstet Gynecol"},{"key":"2025082707172999000_14.3.e239918.3","doi-asserted-by":"publisher","DOI":"10.1097\/00003081-199903000-00007"},{"key":"2025082707172999000_14.3.e239918.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0015-0282(99)00242-3"},{"key":"2025082707172999000_14.3.e239918.5","doi-asserted-by":"publisher","DOI":"10.1097\/01.AOG.0000109218.24211.79"},{"key":"2025082707172999000_14.3.e239918.6","doi-asserted-by":"crossref","first-page":"1283","DOI":"10.1111\/j.1471-0528.2004.00442.x","article-title":"The conservative management of interstitial pregnancy","volume":"111","author":"Jermy","year":"2004","journal-title":"BJOG An Int J Obstet Gynaecol"},{"key":"2025082707172999000_14.3.e239918.7","doi-asserted-by":"publisher","DOI":"10.1002\/uog.1822"},{"key":"2025082707172999000_14.3.e239918.8","doi-asserted-by":"publisher","DOI":"10.1097\/GRF.0b013e31802f4f79"},{"key":"2025082707172999000_14.3.e239918.9","unstructured":"Damario MA . 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