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Although the association of HG and WE was first reported in 1939, it remains an under diagnosed condition with potential for serious and permanent neurological deficits, and some mortality, in both mother and baby. Early recognition of the problem, with timely and careful fluid, electrolyte, glucose and vitamin replacement is needed to avoid complications. We highlight current best practice in the treatment of WE. An open mind to the possibility of HG complications in any pregnant woman presenting with neurological symptoms is probably the most important lesson to learn from the front line.<\/jats:p>","DOI":"10.1136\/bcr-2020-239977","type":"journal-article","created":{"date-parts":[[2021,3,16]],"date-time":"2021-03-16T12:50:40Z","timestamp":1615899040000},"page":"e239977","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Wernicke\u2019s encephalopathy post hyperemesis gravidarum misdiagnosed as Guillain-Barre syndrome: lessons for the frontline"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2057-0970","authenticated-orcid":false,"given":"Kaushiki","family":"Kirty","sequence":"first","affiliation":[{"name":"Internal Medicine, Kasturba Medical College Mangalore, Mangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yashendu","family":"Sarda","sequence":"additional","affiliation":[{"name":"Internal Medicine, Kasturba Medical College Mangalore, Mangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annu","family":"Jacob","sequence":"additional","affiliation":[{"name":"Medicine, Kasturba Medical College Mangalore, Mangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delanthabettu","family":"Venugopala","sequence":"additional","affiliation":[{"name":"Medicine, Kasturba Medical College Mangalore, Mangalore, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,3,16]]},"reference":[{"key":"2025082711044689000_14.3.e239977.1","doi-asserted-by":"publisher","DOI":"10.1007\/s10571-008-9297-7"},{"key":"2025082711044689000_14.3.e239977.2","doi-asserted-by":"publisher","DOI":"10.1177\/0884533611426149"},{"key":"2025082711044689000_14.3.e239977.3","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1177\/0885066616659429","article-title":"Thiamine levels during intensive insulin therapy in critically ill patients","volume":"32","author":"van Snippenburg","year":"2017","journal-title":"J Intensive Care Med"},{"key":"2025082711044689000_14.3.e239977.4","unstructured":"Baynes JW , Dominiczak MH . 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