{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T15:14:25Z","timestamp":1778512465916,"version":"3.51.4"},"reference-count":14,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,2,10]]},"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:p>An 11-year-old boy with a history of atopy and allergic rhinitis under treatment with sublingual immunotherapy was referred following several episodes of food impaction. Diagnosis of eosinophilic oesophagitis, chronic gastritis and gastric mucosa-associated lymphoid tissue (MALT) lymphoma associated to <jats:italic>Helicobacter pylori<\/jats:italic> were confirmed. Results of the extension study were negative and the lymphoma was resolved with eradicating treatment for <jats:italic>H. pylori<\/jats:italic>. No improvement was observed in the oesophagitis after the withdrawal of immunotherapy and treatment with high proton pump inhibitor doses or following the omission of several foods to which subclinical sensitisation was confirmed. Oesophagitis was finally resolved by removing cow's milk protein. After 10 years, neither eosinophilic oesophagitis nor MALT lymphoma was observed.<\/jats:p>\n               <jats:p>Gastric MALT lymphoma associated to <jats:italic>H. pylori<\/jats:italic> is a rare disorder in children. Although coexisting <jats:italic>H. pylori<\/jats:italic> infection is common in patients with eosinophilic oesophagitis, the association of gastric MALT lymphoma with eosinophilic oesophagitis has not been reported before.<\/jats:p>","DOI":"10.1136\/bcr-2020-239980","type":"journal-article","created":{"date-parts":[[2021,3,9]],"date-time":"2021-03-09T10:53:05Z","timestamp":1615287185000},"page":"e239980","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["MALT lymphoma and eosinophilic oesophagitis: incidental finding\u2014 review of possible factors influencing the aetiopathogenesis of eosinophilic oesophagitis"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5817-8301","authenticated-orcid":false,"given":"Beatriz","family":"Fernandez Manso","sequence":"first","affiliation":[{"name":"Pediatric Department, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6103-2191","authenticated-orcid":false,"given":"Josefa","family":"Barrio Torres","sequence":"additional","affiliation":[{"name":"Pediatric Department, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1376-6107","authenticated-orcid":false,"given":"Beatriz","family":"Martinez Escribano","sequence":"additional","affiliation":[{"name":"Pediatric Department, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8227-7465","authenticated-orcid":false,"given":"Cristina","family":"Perez Fernandez","sequence":"additional","affiliation":[{"name":"Pediatric Department, Hospital Universitario de Fuenlabrada, Fuenlabrada, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,3,9]]},"reference":[{"key":"2025082710155022000_14.3.e239980.1","doi-asserted-by":"crossref","first-page":"12818","DOI":"10.3748\/wjg.v20.i36.12818","article-title":"Hematologic manifestations of Helicobacter pylori infection","volume":"20","author":"Campuzano-Maya","year":"2014","journal-title":"World J Gastroenterol"},{"key":"2025082710155022000_14.3.e239980.2","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1002\/pbc.20575","article-title":"Malt lymphoma in children: a report from the NHL-BFM Study Group","volume":"47","author":"Claviez","year":"2006","journal-title":"Pediatr Blood Cancer"},{"key":"2025082710155022000_14.3.e239980.3","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.17219\/acem\/60581","article-title":"Clinical differences of Helicobacter pylori infection in children","volume":"26","author":"Iwa\u0144czak","year":"2017","journal-title":"Adv Clin Exp Med"},{"key":"2025082710155022000_14.3.e239980.4","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s10024-003-3025-6","article-title":"Malt lymphoma in children: case report and review of the literature","volume":"7","author":"Mo","year":"2004","journal-title":"Pediatr Dev Pathol"},{"key":"2025082710155022000_14.3.e239980.5","doi-asserted-by":"crossref","first-page":"2185","DOI":"10.1016\/j.cgh.2019.01.013","article-title":"Association between Helicobacter pylori exposure and decreased odds of eosinophilic Esophagitis-A systematic review and meta-analysis","volume":"17","author":"Shah","year":"2019","journal-title":"Clin Gastroenterol Hepatol"},{"key":"2025082710155022000_14.3.e239980.6","doi-asserted-by":"crossref","first-page":"1244","DOI":"10.1111\/apt.13597","article-title":"Letter: Helicobacter pylori infection and eosinophilic oesophagitis - causal or casual inverse association?","volume":"43","author":"Molina-Infante","year":"2016","journal-title":"Aliment Pharmacol Ther"},{"key":"2025082710155022000_14.3.e239980.7","doi-asserted-by":"crossref","first-page":"60","DOI":"10.3164\/jcbn.13-15","article-title":"Case-Control study of association of eosinophilic gastrointestinal disorders with Helicobacter pylori infection in Japan","volume":"53","author":"Furuta","year":"2013","journal-title":"J Clin Biochem Nutr"},{"key":"2025082710155022000_14.3.e239980.8","doi-asserted-by":"publisher","DOI":"10.1111\/hel.12129"},{"key":"2025082710155022000_14.3.e239980.9","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.anai.2018.12.013","article-title":"Seasonal exacerbation of eosinophilic esophagitis histologic activity in adults and children implicates role of aeroallergens","volume":"122","author":"Reed","year":"2019","journal-title":"Ann Allergy Asthma Immunol"},{"key":"2025082710155022000_14.3.e239980.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2014.08.004"},{"key":"2025082710155022000_14.3.e239980.11","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1016\/j.alit.2018.03.003","article-title":"Development of eosinophilic esophagitis following sublingual immunotherapy with cedar pollen extract: a case report","volume":"67","author":"Kawashima","year":"2018","journal-title":"Allergol Int"},{"key":"2025082710155022000_14.3.e239980.12","doi-asserted-by":"crossref","first-page":"1482","DOI":"10.1016\/j.jaci.2014.01.030","article-title":"Esophageal hypereosinophilia induced by grass sublingual immunotherapy","volume":"133","author":"Antico","year":"2014","journal-title":"J Allergy Clin Immunol"},{"key":"2025082710155022000_14.3.e239980.13","doi-asserted-by":"publisher","DOI":"10.1159\/000355161"},{"key":"2025082710155022000_14.3.e239980.14","doi-asserted-by":"crossref","DOI":"10.1007\/s11882-018-0798-2","article-title":"What is the relationship between eosinophilic esophagitis (EoE) and Aeroallergens? implications for allergen immunotherapy","volume":"18","author":"Egan","year":"2018","journal-title":"Curr Allergy Asthma Rep"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-239980","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:15:59Z","timestamp":1756314959000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-239980"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":14,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,3,9]]},"published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1136\/bcr-2020-239980"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-239980","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3]]}}}