{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:06:28Z","timestamp":1756339588699,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,3,29]]},"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:p>Ozurdex is a dexamethasone intravitreal implant used for the treatment of macular oedema. A rare but serious complication is the migration of the implant into the anterior chamber (AC) in eyes with absent or incomplete posterior capsules that may lead to corneal decompensation. We report the case of a 75-year-old woman who presented with a 1-day history of decreased vision in her left eye. She had a history of complicated cataract surgery and had received multiple Ozurdex implants for postoperative cystoid macular oedema in the same eye. She had significant left corneal decompensation and a mobile Ozurdex implant in the AC. We report a simple but novel surgical technique for removing an Ozurdex implant from the AC using an intravenous cannula (Venflon). This technique can also be applied to removing a fluocinolone acetonide (Iluvien) implant in similar situations.<\/jats:p>","DOI":"10.1136\/bcr-2020-240504","type":"journal-article","created":{"date-parts":[[2021,7,9]],"date-time":"2021-07-09T11:50:27Z","timestamp":1625831427000},"page":"e240504","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Removal of a migrated dexamethasone implant (Ozurdex) from the anterior chamber using an intravenous cannula"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5758-7346","authenticated-orcid":false,"given":"Jae Yee","family":"Ku","sequence":"first","affiliation":[{"name":"Department of Eye and Vision Science, University of Liverpool, Liverpool, UK"},{"name":"Department of Glaucoma, Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karl","family":"Mercieca","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK"},{"name":"Department of Ophthalmology, Universit\u00e4ts-Augenklinik Bonn, Bonn, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth","family":"Yau","sequence":"additional","affiliation":[{"name":"Department of Glaucoma, Manchester Royal Eye Hospital, Manchester University NHS Foundation Trust, Manchester, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,7,9]]},"reference":[{"key":"2025082711415691000_14.7.e240504.1","unstructured":"National Institute for Health and Care Excellence . Dexamethasone intravitreal implant for the treatment of macular oedema secondary to retinal vein occlusion, NICE technology appraisal guidance TA229, 2011. Available: https:\/\/www.nice.org.uk\/Guidance\/TA229 [Accessed 31 Oct 2020]."},{"key":"2025082711415691000_14.7.e240504.2","unstructured":"National Institute for Health and Care Excellence . Dexamethasone intravitreal implant for treating diabetic macular oedema, NICE technology appraisal guidance TA349, 2015. Available: https:\/\/www.nice.org.uk\/guidance\/TA349 [Accessed 31 Oct 2020]."},{"key":"2025082711415691000_14.7.e240504.3","unstructured":"National Institute for Health and Care Excellence . Dexamethasone intravitreal implant for treating non-infectious uveitis, NICE technology appraisal guidance TA460, 2017. Available: https:\/\/www.nice.org.uk\/guidance\/ta460 [Accessed 31 Oct 2020]."},{"key":"2025082711415691000_14.7.e240504.4","doi-asserted-by":"crossref","first-page":"2359","DOI":"10.2147\/DDDT.S138922","article-title":"Widening use of dexamethasone implant for the treatment of macular edema","volume":"11","author":"Bonfiglio","year":"2017","journal-title":"Drug Des Devel Ther"},{"key":"2025082711415691000_14.7.e240504.5","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.ophtha.2013.06.033","article-title":"Dexamethasone implant anterior chamber migration: risk factors, complications, and management strategies","volume":"121","author":"Khurana","year":"2014","journal-title":"Ophthalmology"},{"key":"2025082711415691000_14.7.e240504.6","doi-asserted-by":"crossref","first-page":"246","DOI":"10.1097\/ICU.0000000000000365","article-title":"Anterior segment migration of dexamethasone implant: risk factors, complications, and management","volume":"28","author":"Rahimy","year":"2017","journal-title":"Curr Opin Ophthalmol"},{"key":"2025082711415691000_14.7.e240504.7","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1097\/ICB.0000000000000335","article-title":"Dexamethasone implant removal from anterior chamber: surgical technique","volume":"10","author":"Ruiz-Casas","year":"2016","journal-title":"Retin Cases Brief Rep"},{"key":"2025082711415691000_14.7.e240504.8","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1080\/09273948.2018.1552760","article-title":"Modified no-touch technique for removal of a dexamethasone implant that has migrated to the anterior chamber","volume":"28","author":"Stewart","year":"2020","journal-title":"Ocul Immunol Inflamm"},{"key":"2025082711415691000_14.7.e240504.9","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1097\/ICB.0000000000000284","article-title":"Observation: fluocinolone acetonide (Iluvien) implant migration into the anterior chamber","volume":"11","author":"Papastavrou","year":"2017","journal-title":"Retin Cases Brief Rep"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-240504","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T18:42:02Z","timestamp":1756320122000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-240504"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":9,"journal-issue":{"issue":"7","published-online":{"date-parts":[[2021,7,9]]},"published-print":{"date-parts":[[2021,7]]}},"alternative-id":["10.1136\/bcr-2020-240504"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-240504","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}