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Review of the literature suggest that the clinical semiology and clinical pattern of IBS (urge to defaecate, abdominal pain, abdominal distension, bloating, disturbed sleep and circadian rhythm) simulate the semiology and pattern of RLS. Similarities are also noted in the associated comorbid conditions, effective drugs and proposed hypotheses for both clinical syndromes. We hypothesise that RLS may affect intestine, and IBS-like symptoms in a subset of patients with RLS may be the part of RLS symptoms complex.<\/jats:p>","DOI":"10.1136\/bcr-2020-240686","type":"journal-article","created":{"date-parts":[[2021,3,24]],"date-time":"2021-03-24T12:46:50Z","timestamp":1616590010000},"page":"e240686","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Dopa responsive irritable bowel syndrome: restless bowel syndrome or a gastrointestinal variant of restless legs syndrome?"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7322-904X","authenticated-orcid":false,"given":"Sanjay","family":"Prakash","sequence":"first","affiliation":[{"name":"Neurolgy, Smt BK Shah Medical Institute and Research Centre, Vadodara, Gujarat, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anurag","family":"Prakash","sequence":"additional","affiliation":[{"name":"Parul University Parul Institute of Medical Sciences & Research, Vadodara, Gujarat, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,3,24]]},"reference":[{"key":"2025082706521057000_14.3.e240686.1","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1016\/S2468-1253(20)30217-X","article-title":"Global prevalence of irritable bowel syndrome according to Rome III or IV criteria: a systematic review and meta-analysis","volume":"5","author":"Oka","year":"2020","journal-title":"Lancet Gastroenterol Hepatol"},{"key":"2025082706521057000_14.3.e240686.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2012.02.029"},{"key":"2025082706521057000_14.3.e240686.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2011.05.002"},{"key":"2025082706521057000_14.3.e240686.4","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1007\/s00508-016-1065-y","article-title":"Does frequency of restless legs syndrome and poor sleep quality increase with age in irritable bowel syndrome?","volume":"128","author":"Acay","year":"2016","journal-title":"Wien Klin Wochenschr"},{"key":"2025082706521057000_14.3.e240686.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.sleep.2014.03.025"},{"key":"2025082706521057000_14.3.e240686.6","doi-asserted-by":"crossref","unstructured":"Ford AC , Sperber AD , Corsetti M . 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