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While alpha-3-AChR Ab are most typically associated with thymomas and small cell lung cancer, the presence of these antibodies can suggest a diverse range of other cancers. This case presents a patient with longstanding neuropsychiatric symptoms and possible functional hypothyroidism for whom a low elevation in alpha-3-AChR Ab led to the finding of papillary thyroid carcinoma.<\/jats:p>","DOI":"10.1136\/bcr-2020-240824","type":"journal-article","created":{"date-parts":[[2021,5,27]],"date-time":"2021-05-27T11:17:42Z","timestamp":1622114262000},"page":"e240824","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Nicotinic ganglionic acetylcholine receptor autoantibodies associated with paraneoplastic disease in a neuropsychiatric patient"],"prefix":"10.1136","volume":"14","author":[{"given":"Catherine","family":"Stauffer","sequence":"first","affiliation":[{"name":"Carle Foundation Hospital, Urbana, Illinois, USA"},{"name":"Carle Illinois College of Medicine, University of Illinois at Urbana-Champaign, Champaign, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel A","family":"Llano","sequence":"additional","affiliation":[{"name":"Carle Neuroscience Institute, Carle Foundation Hospital, Urbana, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanna","family":"Kitten","sequence":"additional","affiliation":[{"name":"Psychiatry, Carle Foundation Hospital, Urbana, Illinois, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,5,27]]},"reference":[{"key":"2025082711514470000_14.5.e240824.1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autneu.2008.09.005"},{"key":"2025082711514470000_14.5.e240824.2","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2009.78"},{"key":"2025082711514470000_14.5.e240824.3","unstructured":"Mayo Clinic Laboratories . 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