{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,22]],"date-time":"2026-04-22T00:01:56Z","timestamp":1776816116086,"version":"3.51.2"},"reference-count":7,"publisher":"BMJ","issue":"3","license":[{"start":{"date-parts":[[2021,3,8]],"date-time":"2021-03-08T00:00:00Z","timestamp":1615161600000},"content-version":"unspecified","delay-in-days":7,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,2,15]]},"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:p>A 53-year-old man was admitted for recurrent syncope and found to have complete heart block (CHB). Cardiac magnetic resonance imaging MRI) showed extensive patchy late gadolinium enhancement in the apical and lateral walls, consistent with cardiac sarcoidosis (CS) but no scar in the septum. A fluorodeoxyglucose (FDG)\u2013positron emission tomography showed FDG uptake in the septum and basal lateral walls. Imaging suggested active inflammation in the septum affecting atrioventricular (AV) conduction but no irreversible fibrosis. Diagnosis of isolated CS requires a high level of suspicion and multidisciplinary teamwork involving heart failure specialists, electrophysiologists and rheumatologists. After specialist and patient discussion, treatment of the disease was initiated with prednisone 40\u2009mg daily, 11 months after presenting with CHB. Three weeks later, ECG with pacing inhibited showed second-degree AV block Mobitz type II and 4 weeks later, AV conduction recovery. This highlights the importance of immediate therapy in reversing AV conduction abnormalities in CS.<\/jats:p>","DOI":"10.1136\/bcr-2020-240834","type":"journal-article","created":{"date-parts":[[2021,3,9]],"date-time":"2021-03-09T10:54:20Z","timestamp":1615287260000},"page":"e240834","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Complete heart block in cardiac sarcoidosis reversed by corticosteroid therapy: time course of resolution"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9178-4952","authenticated-orcid":false,"given":"Anna","family":"Tomdio","sequence":"first","affiliation":[{"name":"Cardiovascular Disease, VCU Health, Richmond, Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huzaefah","family":"Syed","sequence":"additional","affiliation":[{"name":"Rheumatology, VCU Health, Richmond, Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth","family":"Ellenbogen","sequence":"additional","affiliation":[{"name":"Cardiovascular Disease, VCU Health, Richmond, Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jordana","family":"Kron","sequence":"additional","affiliation":[{"name":"Cardiovascular Disease, VCU Health, Richmond, Virginia, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,3,9]]},"reference":[{"key":"2025082804082838000_14.3.e240834.1","doi-asserted-by":"crossref","DOI":"10.1161\/CIRCEP.117.006145","article-title":"Outcome of cardiac sarcoidosis presenting with high-grade atrioventricular block","volume":"11","author":"Nordenswan","year":"2018","journal-title":"Circ Arrhythm Electrophysiol"},{"key":"2025082804082838000_14.3.e240834.2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2014.03.043"},{"key":"2025082804082838000_14.3.e240834.3","doi-asserted-by":"publisher","DOI":"10.1111\/jce.12401"},{"key":"2025082804082838000_14.3.e240834.4","doi-asserted-by":"publisher","DOI":"10.1097\/01.md.0000145367.17934.75"},{"key":"2025082804082838000_14.3.e240834.5","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2013.02.004"},{"key":"2025082804082838000_14.3.e240834.6","doi-asserted-by":"crossref","first-page":"42","DOI":"10.17996\/anc.17-00042","article-title":"New guidelines for diagnosis of cardiac sarcoidosis in Japan","volume":"3","author":"Terasaki","year":"2017","journal-title":"Ann Nucl Cardiol"},{"key":"2025082804082838000_14.3.e240834.7","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.ijcard.2017.09.204","article-title":"How common is isolated cardiac sarcoidosis? Extra-cardiac and cardiac findings on clinical examination and whole-body \n                  18\n               F-fluorodeoxyglucose positron emission tomography","volume":"253","author":"Juneau","year":"2018","journal-title":"Int J Cardiol"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-240834","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T11:08:39Z","timestamp":1756379319000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-240834"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":7,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,3,9]]},"published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1136\/bcr-2020-240834"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-240834","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,3]]}}}