{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T03:37:10Z","timestamp":1777347430938,"version":"3.51.4"},"reference-count":13,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,4,20]]},"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:p>Scrub typhus is a zoonosis, which usually manifests as an acute febrile illness. It is caused by a rickettsia, <jats:italic>Orientia tsutsugamushi<\/jats:italic>, which is endemic in the Asian region. It can present with varied clinical manifestations, ranging from acute febrile illness to life-threatening multiorgan dysfunction syndrome. Central nervous system involvement in the form of altered sensorium and\/or meningitis is frequently observed in scrub typhus. However, isolated cranial nerve involvement is uncommon and so far only a few such cases have been reported in the literature. We present a rare case of scrub typhus with fever and diplopia at presentation, which completely improved with doxycycline-based treatment.<\/jats:p>","DOI":"10.1136\/bcr-2020-240882","type":"journal-article","created":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T12:10:20Z","timestamp":1622463020000},"page":"e240882","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Scrub typhus and lateral rectus palsy: an uncommon presentation of a common illness"],"prefix":"10.1136","volume":"14","author":[{"given":"Ajay","family":"Chauhan","sequence":"first","affiliation":[{"name":"Internal Medicine, Civil Hospital, Baddi, Distt Solan, Distt Bilaspur, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6426-0309","authenticated-orcid":false,"given":"Aditya","family":"Jandial","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, PGIMER, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6325-2972","authenticated-orcid":false,"given":"Kundan","family":"Mishra","sequence":"additional","affiliation":[{"name":"Internal Medicine, Army Hospital Research and Referral, New Delhi, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajeev","family":"Sandal","sequence":"additional","affiliation":[{"name":"Radiotherapy and Oncology, Indira Gandhi Medical College Cancer Hospital, Shimla, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,5,31]]},"reference":[{"key":"2025082722154593000_14.5.e240882.1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0006062"},{"key":"2025082722154593000_14.5.e240882.2","first-page":"706","article-title":"Abducens nerve palsy in a patient with scrub typhus: a case report","volume":"30","author":"Bhardwaj","year":"2013","journal-title":"Trop Biomed"},{"key":"2025082722154593000_14.5.e240882.3","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-79-1-26"},{"key":"2025082722154593000_14.5.e240882.4","doi-asserted-by":"publisher","DOI":"10.1093\/trstmh\/trx017"},{"key":"2025082722154593000_14.5.e240882.5","doi-asserted-by":"publisher","DOI":"10.1097\/00001432-200310000-00009"},{"key":"2025082722154593000_14.5.e240882.6","doi-asserted-by":"crossref","DOI":"10.1007\/s13205-020-02389-w","article-title":"Diagnosis of scrub typhus: recent advancements and challenges","volume":"10","author":"Kala","year":"2020","journal-title":"3 Biotech"},{"key":"2025082722154593000_14.5.e240882.7","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/24.3.436"},{"key":"2025082722154593000_14.5.e240882.8","first-page":"88","article-title":"Scrub meningitis complicated by multiple cranial nerve palsies and cerebellitis","volume":"67","author":"Himral","year":"2019","journal-title":"J Assoc Physicians India"},{"key":"2025082722154593000_14.5.e240882.9","first-page":"Od16","article-title":"Scrub typhus presenting with bilateral lateral rectus palsy in a female","volume":"10","author":"Ete","year":"2016","journal-title":"J Clin Diagn Res"},{"key":"2025082722154593000_14.5.e240882.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaapos.2010.06.016"},{"key":"2025082722154593000_14.5.e240882.11","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.55.644.433"},{"key":"2025082722154593000_14.5.e240882.12","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.pediatrneurol.2006.03.008","article-title":"Isolated abducens nerve palsy complicating cytomegalovirus infection","volume":"35","author":"Greco","year":"2006","journal-title":"Pediatr Neurol"},{"key":"2025082722154593000_14.5.e240882.13","doi-asserted-by":"publisher","DOI":"10.1016\/S0887-8994(97)00129-X"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-240882","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:15:52Z","timestamp":1756358152000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-240882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":13,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,5,31]]},"published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1136\/bcr-2020-240882"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-240882","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}