{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T19:10:04Z","timestamp":1756321804993,"version":"3.44.0"},"reference-count":18,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,3,25]]},"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:p>We report a case of 34-year-old clinically asymptomatic woman who had been followed for 6 years for hyperthyroidism with thyroid stimulating hormone &lt;0.006 uIU\/mL, free T4 1.98\u2009ng\/mL, free T3 5.3\u2009pg\/mL, elevated thyroid stimulating immunoglobulin 1.70\u2009IU\/L, thyroid peroxidase antibody 38\u2009IU\/mL and thyroglobulin antibody 9.3\u2009IU\/mL. Radioiodine thyroid scan showed minimal uptake in both thyroid lobes (24-hour uptake was 0.3%). She subsequently underwent evaluation for lower abdominal pain and menstrual irregularities, which revealed a large left ovarian cyst measuring 15.9 cm \u00d7 10.8 cm \u00d7 13.2 cm and right-sided ovarian cyst measuring 2.7 cm \u00d7 3.3 cm \u00d7 3.5 cm. Laparoscopic bilateral ovarian cystectomy was performed and the final pathology revealed struma ovarii of the left ovarian cyst with the entire ovarian tumour made up of benign thyroid tissue. Thyroid function tests performed 3 months after surgical removal of struma ovarii showed euthyroidism. We present a rare case with detailed laboratory and immunological data before and after ovarian extirpation with resolution of hyperthyroidism associated with functional struma ovarii.<\/jats:p>","DOI":"10.1136\/bcr-2020-240924","type":"journal-article","created":{"date-parts":[[2021,4,15]],"date-time":"2021-04-15T13:06:13Z","timestamp":1618491973000},"page":"e240924","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Resolution of hyperthyroidism and thyroid antibodies following struma ovarii resection: an uncommon entity"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0369-1882","authenticated-orcid":false,"given":"Preethi","family":"Padmanaban","sequence":"first","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, The George Washington University, Washington, DC, USA"},{"name":"Department of Endocrinology, Washington DC VA Medical Center, Washington DC, DC, USA"},{"name":"Division of Endocrinology, Department of Medicine, The Medical Faculty Associates, The George Washington University, Washington DC, DC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Nylen","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, The George Washington University, Washington, DC, USA"},{"name":"Department of Endocrinology, Washington DC VA Medical Center, Washington DC, DC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth","family":"Burman","sequence":"additional","affiliation":[{"name":"Department of Medicine, MedStar Washington Hospital Center, Washington, DC, USA"},{"name":"Department of Endocrinology, MedStar Georgetown University Hospital, Washington, DC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabyasachi","family":"Sen","sequence":"additional","affiliation":[{"name":"Division of Endocrinology, Department of Medicine, The George Washington University, Washington, DC, USA"},{"name":"Department of Endocrinology, Washington DC VA Medical Center, Washington DC, DC, USA"},{"name":"Division of Endocrinology, Department of Medicine, The Medical Faculty Associates, The George Washington University, Washington DC, DC, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,4,15]]},"reference":[{"key":"2025082711432490000_14.4.e240924.1","first-page":"116","article-title":"WHO-Klassifikation der Tumoren der Mamma und des weiblichen Genitale: Pathologie und Genetik [WHO classification of breast tumors and tumors of the female genital organs: pathology and genetics]","volume":"86","author":"B\u00f6cker","year":"2002","journal-title":"Verh Dtsch Ges Pathol"},{"key":"2025082711432490000_14.4.e240924.2","doi-asserted-by":"publisher","DOI":"10.1148\/radiographics.21.2.g01mr09475"},{"key":"2025082711432490000_14.4.e240924.3","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-199310000-00008"},{"key":"2025082711432490000_14.4.e240924.4","first-page":"493","article-title":"Struma ovarii","volume":"115","author":"Boettlin","year":"1989","journal-title":"Virchow\u2019s Arch Path Anat"},{"key":"2025082711432490000_14.4.e240924.5","first-page":"134","article-title":"Beitrag Zur Lehre von den Geschwulsten. 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