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We executed a multidisciplinary treatment approach that resulted in a long-term disease-free state. The treatment methods followed in our case could be a successful model to implement by medical practitioners and oral physicians when the situation demands.<\/jats:p>","DOI":"10.1136\/bcr-2020-241010","type":"journal-article","created":{"date-parts":[[2021,5,13]],"date-time":"2021-05-13T13:10:20Z","timestamp":1620911420000},"page":"e241010","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Comprehensive management of major aphthous ulcer"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8019-4690","authenticated-orcid":false,"given":"Aravind","family":"Warrier","sequence":"first","affiliation":[{"name":"Oral Medicine and Radiology, Sri Ramachandra Institute of Higher Education and Research, Chennai, 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