{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T01:24:51Z","timestamp":1787793891153,"version":"build-2784847793"},"reference-count":20,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,5,14]]},"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:p>A 47-\u2009year-old woman developed a rapidly enlarging vulvar mass. Although the clinical appearance suggested malignancy, its lack of atypia and invasion on initial superficial biopsy delayed the pathological diagnosis. It was not until a large incisional biopsy was performed that showed the diagnosis of verrucous squamous cell carcinoma (VSCC) involving pre-existing sinuses of hidradenitis suppurativa (HS). VSCC arising in HS is very rare and often leads to death in published cases. This case demonstrates the challenge in pathological diagnosis of this condition which impacted time to treatment.<\/jats:p>","DOI":"10.1136\/bcr-2020-241075","type":"journal-article","created":{"date-parts":[[2021,6,15]],"date-time":"2021-06-15T12:40:27Z","timestamp":1623760827000},"page":"e241075","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Vulval squamous cell carcinoma arising from hidradenitis suppurrativa"],"prefix":"10.1136","volume":"14","author":[{"given":"Marilyn","family":"Boo","sequence":"first","affiliation":[{"name":"Department of Gynaecological Oncology, Christchurch Women's Hospital, Christchurch, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lois","family":"Eva","sequence":"additional","affiliation":[{"name":"Department of Gynaecological Oncology, Auckland City Hospital, Auckland, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayada","family":"Kellow","sequence":"additional","affiliation":[{"name":"Department of Histopathology, LabPLUS, Auckland, New Zealand"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Scurry","sequence":"additional","affiliation":[{"name":"Pathology North, New Lambton Heights, New South Wales, Australia"},{"name":"University of New South Wales, Sydney, New South Wales, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,6,15]]},"reference":[{"key":"2025082710190817000_14.6.e241075.1","doi-asserted-by":"publisher","DOI":"10.1159\/000269836"},{"key":"2025082710190817000_14.6.e241075.2","doi-asserted-by":"crossref","first-page":"12","DOI":"10.5070\/D3214026278","article-title":"Squamous cell carcinoma in the setting of chronic hidradenitis suppurutiva; report of a patient and update of the literature","volume":"21","author":"Pena","year":"2015","journal-title":"Dermatol Online J"},{"key":"2025082710190817000_14.6.e241075.3","doi-asserted-by":"publisher","DOI":"10.4161\/derm.2.1.12490"},{"key":"2025082710190817000_14.6.e241075.4","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1097\/DSS.0000000000001713","article-title":"Squamous cell carcinoma in perineal, perianal, and gluteal hidradenitis suppurativa: experience in 12 patients","volume":"45","author":"Kohorst","year":"2019","journal-title":"Dermatol Surg"},{"key":"2025082710190817000_14.6.e241075.5","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/j.jdcr.2019.08.025","article-title":"Vulvar squamous cell carcinoma complicating hidradenitis suppurativa in a young woman","volume":"5","author":"Sevray","year":"2019","journal-title":"JAAD Case Rep"},{"key":"2025082710190817000_14.6.e241075.6","first-page":"1022","article-title":"Hidradenitis suppurativa: the third cause of vulva carcinoma","volume":"1","author":"Janse","year":"2017","journal-title":"J Clin Obstet Gynecol Infertil"},{"key":"2025082710190817000_14.6.e241075.7","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1002\/ccr3.2608","article-title":"Fatal outcome of malignant transformation of hidradenitis suppurativa: a case report and literature review","volume":"8","author":"Nielsen","year":"2020","journal-title":"Clin Case Rep"},{"key":"2025082710190817000_14.6.e241075.8","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1016\/j.jaad.2018.10.008","article-title":"Vulvar cancer association with groin hidradenitis suppurativa: a large, urban, midwestern us patient population study","volume":"80","author":"Rastogi","year":"2019","journal-title":"J Am Acad Dermatol"},{"key":"2025082710190817000_14.6.e241075.9","first-page":"86","article-title":"When inflammation shifts to malignancy: extensive squamous cell carcinoma in a female hidradenitis suppurativa\/acne inversa patient","volume":"15","author":"Hessam","year":"2017","journal-title":"J Dtsch Dermatol Ges"},{"key":"2025082710190817000_14.6.e241075.10","first-page":"25","article-title":"Cutaneous squamous cell carcinoma complicating hidradenitis suppurativa: a review of the prevalence, pathogenesis, and treatment of this dreaded complication","volume":"27","author":"Chapman","year":"2018","journal-title":"Acta Dermatovenerol Alp Pannonica Adriat"},{"key":"2025082710190817000_14.6.e241075.11","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1111\/iwj.12671","article-title":"Squamous cell carcinoma complicating a chronic lesion of hidradenitis suppurativa: a case report and review of the literature","volume":"14","author":"Jourabchi","year":"2017","journal-title":"Int Wound J"},{"key":"2025082710190817000_14.6.e241075.12","doi-asserted-by":"crossref","first-page":"e421","DOI":"10.1111\/jdv.14235","article-title":"Advanced squamous cell carcinoma of the axillae mimicking hidradenitis suppurativa","volume":"31","author":"Dessinioti","year":"2017","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2025082710190817000_14.6.e241075.13","article-title":"Carcinoma cuniculatum arising within hidradenitis suppurativa","volume":"29","author":"Falkenhain L\u00f3pez","year":"2020","journal-title":"Exp Dermatol"},{"key":"2025082710190817000_14.6.e241075.14","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1097\/DSS.0000000000001924","article-title":"Commentary on squamous cell carcinoma in perineal, perianal, and gluteal hidradenitis suppurativa","volume":"45","author":"Bennett","year":"2019","journal-title":"Dermatol Surg"},{"key":"2025082710190817000_14.6.e241075.15","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1097\/BCR.0000000000000399","article-title":"Marjolin's ulcer in chronic hidradenitis suppurativa: a rare complication of an often neglected disease","volume":"38","author":"Yon","year":"2017","journal-title":"J Burn Care Res"},{"key":"2025082710190817000_14.6.e241075.16","doi-asserted-by":"publisher","DOI":"10.1007\/s003840000256"},{"key":"2025082710190817000_14.6.e241075.17","article-title":"Study of human papillomavirus presence in gluteal lesions and in squamous cell carcinoma complicating hidradenitis suppurativa","volume":"27","author":"Welfringer","year":"2018","journal-title":"Exp Dermatol"},{"key":"2025082710190817000_14.6.e241075.18","doi-asserted-by":"crossref","first-page":"1449","DOI":"10.1177\/000313481107701131","article-title":"Squamous cell carcinoma complicating chronic suppurative hydradenitis","volume":"77","author":"Losanoff","year":"2011","journal-title":"Am Surg"},{"key":"2025082710190817000_14.6.e241075.19","doi-asserted-by":"crossref","first-page":"5857","DOI":"10.1097\/MD.0000000000005857","article-title":"Successful surgical treatment for squamous cell carcinoma arising from hidradenitis suppurativa","volume":"96","author":"Huang","year":"2017","journal-title":"Medicine"},{"key":"2025082710190817000_14.6.e241075.20","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/DSS.0000000000000944","article-title":"Vulvar, perianal and perineal cancer after hidradenitis suppurativa","volume":"43","author":"Makris","year":"2017","journal-title":"Dermatol Surg"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-241075","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T17:19:15Z","timestamp":1756315155000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-241075"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,6]]},"references-count":20,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2021,6,15]]},"published-print":{"date-parts":[[2021,6]]}},"alternative-id":["10.1136\/bcr-2020-241075"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-241075","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,6]]}}}