{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T07:10:24Z","timestamp":1756278624586,"version":"3.44.0"},"reference-count":5,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,3,7]]},"published-print":{"date-parts":[[2021,3]]},"abstract":"<jats:p>The Epstein-Barr virus (EBV) is highly prevalent throughout the population. Although in most cases, the infection has a good prognosis, it can cause severe complications. We report a case of a healthy child with a primary EBV infection that evolved with two rare complications. She first presented in the emergency room with fever and sore throat, and was diagnosed with tonsillitis and medicated with antibiotic. She returned 7\u2009days later for fatigue, vomiting and abdominal pain. The examination revealed tonsillitis, swollen cervical lymph nodes and pain in the right hypochondrium. An abdominal ultrasound was performed, compatible with acute acalculous cholecystitis. She was admitted in the paediatric nursery and medicated with intravenous antibiotics. The EBV serology revealed primary infection. Two days later, she developed cardiogenic shock and had to be transferred to an intensive care unit under mechanical ventilation and inotropics. She was discharged 12 days later, keeping a moderate left ventricular dysfunction.<\/jats:p>","DOI":"10.1136\/bcr-2020-241099","type":"journal-article","created":{"date-parts":[[2021,3,18]],"date-time":"2021-03-18T13:10:30Z","timestamp":1616073030000},"page":"e241099","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Complicated EBV infection in a healthy child"],"prefix":"10.1136","volume":"14","author":[{"given":"Hugo","family":"Teles","sequence":"first","affiliation":[{"name":"Pediatrics Department, Centro Hospitalar de Setubal EPE, Setubal, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Teresa","family":"Brito","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Centro Hospitalar de Setubal EPE, Setubal, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4337-9658","authenticated-orcid":false,"given":"Joana","family":"Cach\u00e3o","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Centro Hospitalar de Setubal EPE, Setubal, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susana","family":"Parente","sequence":"additional","affiliation":[{"name":"Pediatrics Department, Centro Hospitalar de Setubal EPE, Setubal, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,3,18]]},"reference":[{"key":"2025082623482791000_14.3.e241099.1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2020\/9029601","article-title":"Acute acalculous cholecystitis associated with Epstein-Barr infection: a case report and review of the literature","volume":"2020","author":"Ntelis","year":"2020","journal-title":"Case Rep Med"},{"key":"2025082623482791000_14.3.e241099.2","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/3416857"},{"key":"2025082623482791000_14.3.e241099.3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2015.04.004"},{"key":"2025082623482791000_14.3.e241099.4","first-page":"137","article-title":"Acute Epstein-Barr related myocarditis: an unusual but life-threatening disease in an immunocompetent patient","volume":"21","author":"Watanabe","year":"2020","journal-title":"J Cardiol Cases"},{"key":"2025082623482791000_14.3.e241099.5","first-page":"897","article-title":"Myocarditis as the initial presentation of Epstein-Barr virus infection in a 17-year-old male patient","volume":"65","author":"Ace","year":"2019","journal-title":"Can Fam Physician"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-241099","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T06:48:41Z","timestamp":1756277321000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-241099"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,3]]},"references-count":5,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2021,3,18]]},"published-print":{"date-parts":[[2021,3]]}},"alternative-id":["10.1136\/bcr-2020-241099"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-241099","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2021,3]]}}}