{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T10:29:42Z","timestamp":1760524182951,"version":"3.44.0"},"reference-count":30,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,3,17]]},"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:p>Human bites are an infrequent cause of emergency department visits and hospital admissions. There are rarely published cases of complicated infection, such as infective endocarditis. We present a rare case of a patient with acute infective endocarditis in a healthy native valve and purulent pericarditis from a human bite. A 40-year-old man with obesity suffered deep human bites by an adult woman, with two deep lesions in the anterior thorax and one superficial lesion in the upper abdomen and admitted in intensive care unit with septic shock and a persistent aortic murmur. Echocardiography described evidence of vegetation, perforation and severe regurgitation of aortic valve. Scanner described moderate pericardial effusion. Cardiac surgery was performed, with evidence of purulent pericardial effusion after pericardiotomy, and subsequently aortic valve replacement with a 25\u2009mm bioprosthesis. The patient showed positive progress.<\/jats:p>","DOI":"10.1136\/bcr-2020-241264","type":"journal-article","created":{"date-parts":[[2021,4,9]],"date-time":"2021-04-09T12:41:33Z","timestamp":1617972093000},"page":"e241264","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Human bite wounds as a portal of entry for infective endocarditis and purulent pericarditis: a very rare association"],"prefix":"10.1136","volume":"14","author":[{"given":"Miguel","family":"Oyonarte G\u00f3mez","sequence":"first","affiliation":[{"name":"Cardiovascular Center, Hospital Clinico San Borja Arriaran, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8228-0565","authenticated-orcid":false,"given":"Cesar","family":"Del Castillo Gordillo","sequence":"additional","affiliation":[{"name":"Cardiovascular Center, Hospital Clinico San Borja Arriaran, Santiago, Chile"},{"name":"Cardiovascular Center, Hospital DIPRECA, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"Rojas Romero","sequence":"additional","affiliation":[{"name":"Cardiovascular Center, Hospital Clinico San Borja Arriaran, Santiago, Chile"},{"name":"Intermal Medicine and cardiology, Hospital Provincial del Huasco, Vallenar, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenyin","family":"Loo Urbina","sequence":"additional","affiliation":[{"name":"Internal Medicine, University of Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,4,9]]},"reference":[{"key":"2025082709304129000_14.4.e241264.1","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2700.55331"},{"key":"2025082709304129000_14.4.e241264.2","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1017\/S1481803500015475","article-title":"Factors associated with delay to emergency department presentation, antibiotic usage and admission for human bite injuries","volume":"9","author":"Merchant","year":"2007","journal-title":"CJEM"},{"key":"2025082709304129000_14.4.e241264.3","doi-asserted-by":"publisher","DOI":"10.1053\/ajem.2002.31146"},{"key":"2025082709304129000_14.4.e241264.4","first-page":"433","article-title":"Animal and human bite wounds","volume":"112","author":"Rothe","year":"2015","journal-title":"Dtsch Arztebl Int"},{"key":"2025082709304129000_14.4.e241264.5","doi-asserted-by":"publisher","DOI":"10.1086\/379331"},{"key":"2025082709304129000_14.4.e241264.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)90838-7"},{"key":"2025082709304129000_14.4.e241264.7","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)92049-N"},{"key":"2025082709304129000_14.4.e241264.8","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)92876-6"},{"key":"2025082709304129000_14.4.e241264.9","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-009-0055-x"},{"key":"2025082709304129000_14.4.e241264.10","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(76)80628-2"},{"key":"2025082709304129000_14.4.e241264.11","doi-asserted-by":"publisher","DOI":"10.1086\/313753"},{"key":"2025082709304129000_14.4.e241264.12","doi-asserted-by":"crossref","first-page":"1517","DOI":"10.4067\/S0034-98872012001200001","article-title":"Endocarditis infecciosa: caracter\u00edsticas cl\u00ednicas, complicaciones Y mortalidad en 506 pacientes Y factores pron\u00f3sticos de sobrevida a 10 a\u00f1os (1998-2008). 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