{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T23:14:25Z","timestamp":1791501265576,"version":"4.3.4"},"reference-count":10,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,1,27]]},"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:p>We describe a case of a young man, taking no other routine medications, presenting with erythema multiforme and cetirizine-induced psychosis with re-challenge evidence. On retrospective elicitation of history, it was found that he had been involved in a motor vehicle collision 4 months prior and was a daily cannabis user; there were no objective abnormalities by MRI and neurological evaluations. Although rare, cetirizine-induced psychosis is an important adverse drug reaction that warrants the attention of healthcare practitioners.<\/jats:p>","DOI":"10.1136\/bcr-2020-241393","type":"journal-article","created":{"date-parts":[[2021,2,5]],"date-time":"2021-02-05T16:30:56Z","timestamp":1612542656000},"page":"e241393","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Cetirizine-induced psychosis in a young adult with erythema multiforme"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4637-2291","authenticated-orcid":false,"given":"David","family":"Croitoru","sequence":"first","affiliation":[{"name":"Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada"},{"name":"Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephanie G","family":"Brooks","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincent","family":"Piguet","sequence":"additional","affiliation":[{"name":"Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada"},{"name":"Department of Medicine, Women\u2019s College Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lindsey","family":"MacGillivray","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada"},{"name":"Department of Psychiatry, University Health Network, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,2,5]]},"reference":[{"key":"2025082722531518000_14.2.e241393.1","unstructured":"Naqvi A , Gerriets V . Cetirizine. In: StatPearls [Internet]. Treasure Island, FL: StatPearls Publishing, 2020. https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK549776\/"},{"key":"2025082722531518000_14.2.e241393.2","doi-asserted-by":"crossref","first-page":"219","DOI":"10.4103\/0019-5154.110832","article-title":"Pharmacology of antihistamines","volume":"58","author":"Church","year":"2013","journal-title":"Indian J Dermatol"},{"key":"2025082722531518000_14.2.e241393.3","unstructured":"Wolverton Stephen E , Wu JJ . Comprehensive dermatologic drug therapy. 4th edn. Philadelphia, PA: Elsevier, 2020."},{"key":"2025082722531518000_14.2.e241393.4","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.55.646.556"},{"key":"2025082722531518000_14.2.e241393.5","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1176\/appi.psy.45.1.89","article-title":"Promethazine-Induced psychosis in a 16-year-old girl","volume":"45","author":"Timnak","year":"2004","journal-title":"Psychosomatics"},{"key":"2025082722531518000_14.2.e241393.6","doi-asserted-by":"crossref","first-page":"548","DOI":"10.1016\/S0735-6757(97)90212-6","article-title":"Diphenhydramine-induced psychosis with therapeutic doses","volume":"15","author":"Sexton","year":"1997","journal-title":"Am J Emerg Med"},{"key":"2025082722531518000_14.2.e241393.7","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1097\/WNF.0b013e318290b9b2","article-title":"Cetirizine-associated delusions and depression in an 18-year-old woman","volume":"36","author":"Garden","year":"2013","journal-title":"Clin Neuropharmacol"},{"key":"2025082722531518000_14.2.e241393.8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2007.02229.x"},{"key":"2025082722531518000_14.2.e241393.9","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1007\/s12016-017-8667-7","article-title":"Current perspectives on erythema multiforme","volume":"54","author":"Lerch","year":"2018","journal-title":"Clin Rev Allergy Immunol"},{"key":"2025082722531518000_14.2.e241393.10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0114336","article-title":"Central nervous system effects of the second-generation antihistamines marketed in Japan--review of inter-drug differences using the proportional impairment ratio (PIR)-","volume":"9","author":"Isomura","year":"2014","journal-title":"PLoS One"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2020-241393","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T05:53:25Z","timestamp":1756360405000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2020-241393"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,2]]},"references-count":10,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2021,2,5]]},"published-print":{"date-parts":[[2021,2]]}},"alternative-id":["10.1136\/bcr-2020-241393"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2020-241393","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,2]]}}}