{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:03:04Z","timestamp":1756425784918,"version":"3.44.0"},"reference-count":19,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,3,19]]},"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:p>Ewing\u2019s sarcoma is an aggressive tumour, common in paediatric age, in which treatment often implies a decrease in reproductive potential. We describe a case of a woman who had a lumbar Ewing\u2019s Sarcoma in 1991, at the age of 8. She was submitted to extended tumourectomy, chemotherapy and local radiotherapy without preservation techniques. In adult life, and after two in vitro fertilization (IVF) reproductive cycles without success, she spontaneously conceived at the age of 32. After an uneventful pregnancy, she delivered a healthy child by caesarean section. This is a rare successful case of a spontaneous and uneventful pregnancy without previous preservation techniques. In the last 30 years, there has been significant development in this area, and currently, there are solutions for these patients, including in prepubertal age.<\/jats:p>","DOI":"10.1136\/bcr-2020-241417","type":"journal-article","created":{"date-parts":[[2021,4,8]],"date-time":"2021-04-08T12:47:56Z","timestamp":1617886076000},"page":"e241417","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Surviving cancer or future motherhood? Both are possible: an Ewing sarcoma case in an 8-year-old girl"],"prefix":"10.1136","volume":"14","author":[{"given":"T\u00e2nia","family":"Ascens\u00e3o","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria In\u00eas","family":"Marques","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena Barros","family":"Leite","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Centro Hospitalar e Universitario de Coimbra EPE, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,4,8]]},"reference":[{"key":"2025082801141192000_14.4.e241417.1","doi-asserted-by":"crossref","first-page":"e79","DOI":"10.1016\/j.jpag.2014.06.009","article-title":"Successful pregnancy after sacrectomy combined with chemotherapy and radiation for Ewing sarcoma: case report and literature review","volume":"28","author":"Kakogawa","year":"2015","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"2025082801141192000_14.4.e241417.2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1038\/s41572-018-0003-x","article-title":"Ewing sarcoma","volume":"4","author":"Gr\u00fcnewald","year":"2018","journal-title":"Nat Rev Dis Primers"},{"key":"2025082801141192000_14.4.e241417.3","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1590\/S0102-36162012000400007","article-title":"Ewing's sarcoma: epidemiology and prognosis for patients treated at the pediatric oncology Institute, IOP-GRAACC-UNIFESP","volume":"47","author":"Bellan","year":"2012","journal-title":"Rev Bras Ortop"},{"key":"2025082801141192000_14.4.e241417.4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2003.08.022"},{"key":"2025082801141192000_14.4.e241417.5","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.11891"},{"key":"2025082801141192000_14.4.e241417.6","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1111\/aogs.13616","article-title":"Ovarian tissue cryopreservation for fertility preservation in 418 girls and adolescents up to 15\u00a0years of age facing highly gonadotoxic treatment. 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