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Clinicians should be familiar with this problem as it can have life-threatening consequences and lead to important changes in patient\u2019s management. Our patient was admitted for acute delirium with an ECG showing atrial fibrillation with wide QRS and ST-segment elevation. These modifications were first mistaken for an acute myocardial infarction and a diagnosis of Brugada syndrome was finally reached. Treatment after the acute phase implied changes in the therapeutic modality and required frequent monitoring.<\/jats:p>","DOI":"10.1136\/bcr-2021-241555","type":"journal-article","created":{"date-parts":[[2021,6,9]],"date-time":"2021-06-09T11:45:40Z","timestamp":1623239140000},"page":"e241555","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Lithium-induced ECG modifications: navigating from acute coronary syndrome to Brugada syndrome"],"prefix":"10.1136","volume":"14","author":[{"given":"L\u00e9onard","family":"Diserens","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Hopital Riviera-Chablais, Rennaz, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandra Pia","family":"Porretta","sequence":"additional","affiliation":[{"name":"Department of Cardiology, CHUV, Lausanne, Switzerland"},{"name":"Department of Clinical-Surgical, Diagnostic and Pediatric Science, University of Pavia, Pavia, Lombardia, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catalina","family":"Trana","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hopital Riviera-Chablais, Rennaz, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Meier","sequence":"additional","affiliation":[{"name":"Department of Cardiology, CHUV, Lausanne, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,6,9]]},"reference":[{"key":"2025082802173691000_14.6.e241555.1","doi-asserted-by":"crossref","first-page":"1174","DOI":"10.1038\/npp.2017.238","article-title":"The new news about lithium: an underutilized treatment in the United States","volume":"43","author":"Post","year":"2018","journal-title":"Neuropsychopharmacology"},{"key":"2025082802173691000_14.6.e241555.2","doi-asserted-by":"crossref","first-page":"1363","DOI":"10.1002\/clc.22822","article-title":"Lithium-Induced electrocardiographic changes: a complete review","volume":"40","author":"Mehta","year":"2017","journal-title":"Clin Cardiol"},{"key":"2025082802173691000_14.6.e241555.3","first-page":"179","article-title":"Atypical arrhythmia associated with lithium therapy: when to expect the unexpected?","volume":"35","author":"Iorgoveanu","year":"2019","journal-title":"Acta Cardiol Sin"},{"key":"2025082802173691000_14.6.e241555.4","unstructured":"Kalcik MDM , Gursoy MD O O , Keles MDN . 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