{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T13:41:26Z","timestamp":1783690886577,"version":"3.55.0"},"reference-count":15,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,4,18]]},"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:p>Side port infection and corneal abscess after cataract surgery can produce devastating outcomes. Topical antibacterial drugs are the mainstay in management of these cases. Although intrastromal antifungal agents are an established modality for fungal keratitis, such use of antibacterial agents is rarely reported due to better pharmacokinetic profile of antibacterial agents.<\/jats:p>\n               <jats:p>We report a case of methicillin-resistant <jats:italic>Staphylococcus aureus<\/jats:italic> corneal abscess following phacoemulsification that responded to intrastromal vancomycin injection in addition to conventional therapy.<\/jats:p>\n               <jats:p>This case of postphacoemulsification corneal abscess highlights the importance of postoperative hygiene practices, use of anterior segment optical coherence tomography for monitoring these patients and use of intrastromal vancomycin as an adjunct to topical and systemic therapy.<\/jats:p>","DOI":"10.1136\/bcr-2021-241709","type":"journal-article","created":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T11:55:53Z","timestamp":1621857353000},"page":"e241709","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Role of intrastromal vancomycin in recalcitrant corneal abscess after phacoemulsification"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0125-2811","authenticated-orcid":false,"given":"Mohit","family":"Chhabra","sequence":"first","affiliation":[{"name":"Ophthalmology, Maulana Azad Medical College, New Delhi, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6944-7466","authenticated-orcid":false,"given":"Ruchi","family":"Goel","sequence":"additional","affiliation":[{"name":"Ophthalmology, Maulana Azad Medical College, New Delhi, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6530-3390","authenticated-orcid":false,"given":"Samreen","family":"Khanam","sequence":"additional","affiliation":[{"name":"Ophthalmology, Maulana Azad Medical College, New Delhi, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonam","family":"Singh","sequence":"additional","affiliation":[{"name":"Ophthalmology, Maulana Azad Medical College, New Delhi, Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,5,24]]},"reference":[{"key":"2025082702195765000_14.5.e241709.1","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.survophthal.2020.08.004","article-title":"Surgical alternatives to keratoplasty in microbial keratitis","volume":"66","author":"Singhal","year":"2021","journal-title":"Surv Ophthalmol"},{"key":"2025082702195765000_14.5.e241709.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(95)30771-3"},{"key":"2025082702195765000_14.5.e241709.3","doi-asserted-by":"crossref","first-page":"1702","DOI":"10.1016\/j.jcrs.2005.02.033","article-title":"Spectrum of clear corneal incision cataract wound infection","volume":"31","author":"Kehdi","year":"2005","journal-title":"J Cataract Refract Surg"},{"key":"2025082702195765000_14.5.e241709.4","doi-asserted-by":"crossref","first-page":"1761","DOI":"10.1016\/S0161-6420(91)32053-0","article-title":"A case-control study of risk factors for postoperative endophthalmitis","volume":"98","author":"Menikoff","year":"1991","journal-title":"Ophthalmology"},{"key":"2025082702195765000_14.5.e241709.5","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90250-6"},{"key":"2025082702195765000_14.5.e241709.6","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1001\/archopht.119.12.1755","article-title":"Clear corneal wound infection after phacoemulsification","volume":"119","author":"Cosar","year":"2001","journal-title":"Arch Ophthalmol"},{"key":"2025082702195765000_14.5.e241709.7","doi-asserted-by":"crossref","first-page":"100838","DOI":"10.1016\/j.ajoc.2020.100838","article-title":"Autologous platelet-rich plasma in the treatment of refractory corneal ulcers: a case report","volume":"20","author":"Rechichi","year":"2020","journal-title":"Am J Ophthalmol Case Rep"},{"key":"2025082702195765000_14.5.e241709.8","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.jcrs.2011.03.005","article-title":"Intrastromal injection of antibiotic agent in the management of recalcitrant bacterial keratitis","volume":"37","author":"Liang","year":"2011","journal-title":"J Cataract Refract Surg"},{"key":"2025082702195765000_14.5.e241709.9","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1007\/s10792-021-01696-2","article-title":"Comparison of the effect of teicoplanin and vancomycin on experimental methicillin-resistant Staphylococcus aureus keratitis","volume":"41","author":"Ucgul","year":"2021","journal-title":"Int Ophthalmol"},{"key":"2025082702195765000_14.5.e241709.10","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1097\/ICO.0b013e3181d403d4","article-title":"Infectious crystalline keratopathy treated with intrastromal antibiotics","volume":"29","author":"Khan","year":"2010","journal-title":"Cornea"},{"key":"2025082702195765000_14.5.e241709.11","doi-asserted-by":"publisher","DOI":"10.4321\/S0365-66912009000300004"},{"key":"2025082702195765000_14.5.e241709.12","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1038\/sj.eye.6701836","article-title":"Acute Staphylococcus aureus wound infection after temporal clear corneal phacoemulsification","volume":"20","author":"Wong","year":"2006","journal-title":"Eye"},{"key":"2025082702195765000_14.5.e241709.13","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1097\/01.ICL.0000133241.56713.2F","article-title":"Corneal intrastromal gatifloxacin crystal deposits after penetrating keratoplasty","volume":"30","author":"Awwad","year":"2004","journal-title":"Eye Contact Lens"},{"key":"2025082702195765000_14.5.e241709.14","doi-asserted-by":"publisher","DOI":"10.4103\/0301-4738.40368"},{"key":"2025082702195765000_14.5.e241709.15","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.87.7.834"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-241709","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:20:05Z","timestamp":1756286405000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-241709"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":15,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,5,24]]},"published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1136\/bcr-2021-241709"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-241709","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}