{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T00:02:40Z","timestamp":1756425760912,"version":"3.44.0"},"reference-count":14,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,6,10]]},"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:p>Cutaneous angiosarcoma is a type of rare and locally aggressive malignancy requiring individualised treatment owing to paucity of randomised trials. We present the case of a middle-aged cancer survivor with locally advanced angiosarcoma of scalp managed with surgery, radiotherapy, chemotherapy and targeted therapy over a course of 6\u2009years for two recurrences. The first recurrence was preceded by opsoclonus myoclonus syndrome, a type of paraneoplastic neurological syndrome (PNS), rarely reported in sarcomas. The second recurrence had a rapid clinical course, which led to a therapeutic dilemma of best supportive care versus active management. A trial of weekly paclitaxel was started that was continued for a total of 12 cycles with good objective clinical response. Presently, he is tolerating maintenance pazopanib well and is symptom free for 6 months. In cutaneous angiosarcoma patients, PNS may be a harbinger of recurrence and aggressive, multimodality treatment helps prolong survival.<\/jats:p>","DOI":"10.1136\/bcr-2021-241824","type":"journal-article","created":{"date-parts":[[2021,6,25]],"date-time":"2021-06-25T12:35:37Z","timestamp":1624624537000},"page":"e241824","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Recurrent angiosarcoma of scalp with opsoclonus myoclonus syndrome: role of salvage treatment"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7440-0996","authenticated-orcid":false,"given":"Kannan","family":"Periasamy","sequence":"first","affiliation":[{"name":"Department of Radiotherapy and Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5861-959X","authenticated-orcid":false,"given":"Namrata","family":"Das","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy and Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Divya","family":"Khosla","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy and Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rakesh","family":"Kapoor","sequence":"additional","affiliation":[{"name":"Department of Radiotherapy and Oncology, Postgraduate Institute of Medical Education and Research, Chandigarh, India"},{"name":"Director, Homi Bhabha Cancer Hospital, Sangrur, 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