{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T06:54:04Z","timestamp":1785480844035,"version":"3.56.0"},"reference-count":26,"publisher":"BMJ","issue":"5","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/bmj.com\/coronavirus\/usage"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,4,5]]},"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:p>This report documents a rare case of COVID-19-associated constrictive pericarditis (CP) in the setting of a recent COVID-19 infection. A 55-year-old man with a history of hypertension and gout presented with acute hypoxic respiratory failure and was diagnosed with COVID-19 pneumonia with progression to acute respiratory distress syndrome. His hospital course was complicated by a large pericardial effusion; an emergent bedside transthoracic echocardiography was concerning for cardiac tamponade, so pericardiocentesis was performed. A workup with cardiac magnetic resonance imaging showed changes consistent with a diagnosis of CP. Viral and idiopathic aetiologies are the most common cause of CP in the developed world, with COVID-19 now a proposed predisposing viral illness. The virus induces systemic inflammation and pericardial changes that can lead to CP physiology. Imaging modalities including echocardiogram and cardiac magnetic resonance play an integral role in confirming the diagnosis.<\/jats:p>","DOI":"10.1136\/bcr-2021-242018","type":"journal-article","created":{"date-parts":[[2021,5,11]],"date-time":"2021-05-11T12:46:09Z","timestamp":1620737169000},"page":"e242018","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":13,"title":["Coronavirus disease 2019 (COVID-19)-associated constrictive pericarditis"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1967-3662","authenticated-orcid":false,"given":"Jennifer Kate","family":"Beckerman","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, George Washington University School of Medicine, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Alarfaj","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, George Washington University School of Medicine, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia M","family":"Tracy","sequence":"additional","affiliation":[{"name":"Division of Cardiology, George Washington University School of Medicine, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariel D","family":"Faiwiszewski","sequence":"additional","affiliation":[{"name":"Division of Cardiology, George Washington University School of Medicine, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew D","family":"Choi","sequence":"additional","affiliation":[{"name":"Division of Cardiology and Department of Radiology, George Washington University School of Medicine, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,5,11]]},"reference":[{"key":"2025082702561928000_14.5.e242018.1","unstructured":"WHO . COVID-19 Weekly epidemiological update, 2021. Available: https:\/\/www.who.int\/publications\/m\/item\/weekly-epidemiological-update-12-january-2021 [Accessed 19 Jan 2021]."},{"key":"2025082702561928000_14.5.e242018.2","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.hjc.2020.05.004","article-title":"Involvement of cardiovascular system as the critical point in coronavirus disease 2019 (COVID-19) prognosis and recovery","volume":"61","author":"Lazaridis","year":"2020","journal-title":"Hellenic J Cardiol"},{"key":"2025082702561928000_14.5.e242018.3","article-title":"Acute pericarditis and cardiac tamponade in a patient with COVID-19: a therapeutic challenge","volume":"7","author":"Asif","year":"2020","journal-title":"Eur J Case Rep Intern Med"},{"key":"2025082702561928000_14.5.e242018.4","doi-asserted-by":"crossref","DOI":"10.3390\/v12040372","article-title":"Virology, epidemiology, pathogenesis, and control of COVID-19","volume":"12","author":"Jin","year":"2020","journal-title":"Viruses"},{"key":"2025082702561928000_14.5.e242018.5","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv318"},{"key":"2025082702561928000_14.5.e242018.6","first-page":"2021","article-title":"Cardiac tamponade in a patient with myocardial infarction and COVID-19: electron microscopy","volume":"2","author":"Garc\u00eda-Cruz","year":"2020","journal-title":"Case Reports"},{"key":"2025082702561928000_14.5.e242018.7","first-page":"1-7","article-title":"Pericardial effusion in patients with COVID-19: case series","volume":"4","author":"Sauer","year":"2020","journal-title":"Eur Heart J Case Rep"},{"key":"2025082702561928000_14.5.e242018.8","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.ejim.2020.04.045","article-title":"SARS-CoV-2 detection in the pericardial fluid of a patient with cardiac tamponade","volume":"76","author":"Farina","year":"2020","journal-title":"Eur J Intern Med"},{"key":"2025082702561928000_14.5.e242018.9","doi-asserted-by":"crossref","first-page":"802","DOI":"10.1177\/2150135120949455","article-title":"Pediatric COVID-19 and pericarditis presenting with acute pericardial tamponade","volume":"11","author":"Raymond","year":"2020","journal-title":"World J Pediatr Congenit Heart Surg"},{"key":"2025082702561928000_14.5.e242018.10","first-page":"e9074","article-title":"Acute effusive pericarditis: a late complication of COVID-19","volume":"12","author":"Fox","year":"2020","journal-title":"Cureus"},{"key":"2025082702561928000_14.5.e242018.11","doi-asserted-by":"crossref","DOI":"10.12659\/AJCR.925554","article-title":"Acute myopericarditis with pericardial effusion and cardiac tamponade in a patient with COVID-19","volume":"21","author":"Purohit","year":"2020","journal-title":"Am J Case Rep"},{"key":"2025082702561928000_14.5.e242018.12","doi-asserted-by":"crossref","DOI":"10.1093\/eurheartj\/ehaa253","article-title":"Life-Threatening cardiac tamponade complicating myo-pericarditis in COVID-19","volume":"41","author":"Hua","year":"2020","journal-title":"Eur Heart J"},{"key":"2025082702561928000_14.5.e242018.13","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2017-311683"},{"key":"2025082702561928000_14.5.e242018.14","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1007\/s10557-020-07044-3","article-title":"Anakinra for the treatment of COVID-19-Associated pericarditis: a case report","volume":"34","author":"Karadeniz","year":"2020","journal-title":"Cardiovasc Drugs Ther"},{"key":"2025082702561928000_14.5.e242018.15","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2020-237617","article-title":"Acute pericarditis as a primary presentation of COVID-19","volume":"13","author":"Kumar","year":"2020","journal-title":"BMJ Case Rep"},{"key":"2025082702561928000_14.5.e242018.16","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.medcle.2020.06.001","article-title":"Acute pericarditis due to COVID-19 infection: an underdiagnosed disease?","volume":"155","author":"Tung-Chen","year":"2020","journal-title":"Medicina Clinica (English Ed.)."},{"key":"2025082702561928000_14.5.e242018.17","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.ijid.2020.09.1440","article-title":"Acute pericarditis and severe acute respiratory syndrome coronavirus 2: case report","volume":"101","author":"Blagojevic","year":"2020","journal-title":"Int J Infect Dis"},{"key":"2025082702561928000_14.5.e242018.18","doi-asserted-by":"crossref","unstructured":"Naqvi SGZ , Naseeb U , Fatima K , et al . Acute pericarditis and pericardial effusion in a hypertensive COVID-19 patient. Cureus 2020;9.doi:10.7759\/cureus.10705","DOI":"10.7759\/cureus.10705"},{"key":"2025082702561928000_14.5.e242018.19","doi-asserted-by":"crossref","DOI":"10.1016\/j.tmaid.2020.101863","article-title":"Pericarditis in a young internal medicine resident with COVID-19 in Colombia","volume":"37","author":"Ortiz-Mart\u00ednez","year":"2020","journal-title":"Travel Med Infect Dis"},{"key":"2025082702561928000_14.5.e242018.20","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.2020200274"},{"key":"2025082702561928000_14.5.e242018.21","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1097\/RLI.0000000000000672","article-title":"The clinical and chest CT features associated with severe and critical COVID-19 pneumonia","volume":"55","author":"Li","year":"2020","journal-title":"Invest Radiol"},{"key":"2025082702561928000_14.5.e242018.22","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1016\/j.jcmg.2020.05.004","article-title":"Cardiac involvement in patients recovered from COVID-2019 identified using magnetic resonance imaging","volume":"13","author":"Huang","year":"2020","journal-title":"JACC Cardiovasc Imaging"},{"key":"2025082702561928000_14.5.e242018.23","doi-asserted-by":"crossref","first-page":"1265","DOI":"10.1001\/jamacardio.2020.3557","article-title":"Outcomes of cardiovascular magnetic resonance imaging in patients recently recovered from coronavirus disease 2019 (COVID-19).","volume":"5","author":"Puntmann","year":"2020","journal-title":"JAMA Cardiology"},{"key":"2025082702561928000_14.5.e242018.24","doi-asserted-by":"crossref","unstructured":"Russell B , Moss C , Rigg A , et al . COVID-19 and treatment with NSAIDs and corticosteroids: should we be limiting their use in the clinical setting? Ecancermedicalscience 2020;14.doi:10.3332\/ecancer.2020.1023","DOI":"10.3332\/ecancer.2020.1023"},{"key":"2025082702561928000_14.5.e242018.25","doi-asserted-by":"crossref","first-page":"625","DOI":"10.2459\/JCM.0000000000001059","article-title":"Anti-Inflammatory therapies for pericardial diseases in the COVID-19 pandemic: safety and potentiality","volume":"21","author":"Imazio","year":"2020","journal-title":"J Cardiovasc Med"},{"key":"2025082702561928000_14.5.e242018.26","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000022093","article-title":"Symptomatic pericardial effusion in the setting of asymptomatic COVID-19 infection: a case report","volume":"99","author":"Amoozgar","year":"2020","journal-title":"Medicine"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-242018","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:56:59Z","timestamp":1756288619000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-242018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":26,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,5,11]]},"published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1136\/bcr-2021-242018"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-242018","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}