{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T22:11:58Z","timestamp":1793052718345,"version":"4.5.0"},"reference-count":10,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,5,2]]},"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:p>Hypoglossal nerve schwannomas originating extracranially and mimicking a submandibular salivary gland tumour are extremely rare. A 55-year-old woman presented with a painless, gradually increasing swelling in the right submandibular region for the past 1\u2009year. Fine-needle aspiration cytology and contrast-enhanced CT of the swelling showed features of submandibular gland malignant lesion. Intraoperatively, the right submandibular gland with a hypoglossal nerve swelling was noticed. Right submandibular gland along with the hypoglossal swelling were excised with adequate margins. However, the postoperative histopathology was reported as hypoglossal nerve schwannoma and a normal salivary gland. Accurate preoperative diagnosis of hypoglossal schwannomas may be challenging. A high level of suspicion must be sought for in cases with unusual clinical presentations and imaging characteristics. Herein, we report a rare presentation of submandibular hypoglossal schwannoma along with its clinical features and its management.<\/jats:p>","DOI":"10.1136\/bcr-2021-242225","type":"journal-article","created":{"date-parts":[[2021,5,26]],"date-time":"2021-05-26T14:36:42Z","timestamp":1622039802000},"page":"e242225","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Hypoglossal schwannoma in the submandibular region"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7324-5012","authenticated-orcid":false,"given":"Aparna","family":"Das","sequence":"first","affiliation":[{"name":"ENT, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7065-0258","authenticated-orcid":false,"given":"Sivaraman","family":"Ganesan","sequence":"additional","affiliation":[{"name":"ENT, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalaiarasi","family":"Raja","sequence":"additional","affiliation":[{"name":"ENT, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1026-4678","authenticated-orcid":false,"given":"Arun","family":"Alexander","sequence":"additional","affiliation":[{"name":"ENT, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2021,5,26]]},"reference":[{"key":"2025082702075698000_14.5.e242225.1","first-page":"288","article-title":"Schwannoma of the hypoglossal nerve: review of the literature based on an illustrative case","volume":"7","author":"Fornaro","year":"2017","journal-title":"Molecular and Clinical Oncology"},{"key":"2025082702075698000_14.5.e242225.2","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1227\/NEU.0b013e31822a547b","article-title":"Microsurgical management of hypoglossal schwannomas over 3 decades: a modified grading scale to guide surgical approach","volume":"69","author":"Nonaka","year":"2011","journal-title":"Operative Neurosurgery"},{"key":"2025082702075698000_14.5.e242225.3","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1017\/S0022215100124892","article-title":"Submaxillary hypoglossal neurilemmoma","volume":"107","author":"Sutay","year":"1993","journal-title":"J. Laryngol. Otol."},{"key":"2025082702075698000_14.5.e242225.4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2012\/842761","article-title":"Hypoglossal schwannoma masquerading as a carotid body tumor","volume":"2012","author":"Lee","year":"2012","journal-title":"Case Rep Otolaryngol"},{"key":"2025082702075698000_14.5.e242225.5","doi-asserted-by":"publisher","DOI":"10.1227\/00006123-198205000-00013"},{"key":"2025082702075698000_14.5.e242225.6","doi-asserted-by":"publisher","DOI":"10.1002\/dc.20449"},{"key":"2025082702075698000_14.5.e242225.7","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.2214\/AJR.17.18102","article-title":"Hypoglossal canal lesions: distinctive imaging features and simple diagnostic algorithm","volume":"209","author":"Weindling","year":"2017","journal-title":"American Journal of Roentgenology"},{"key":"2025082702075698000_14.5.e242225.8","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.jocn.2018.11.037","article-title":"Hypoglossal schwannomas: a systematic review of the literature","volume":"62","author":"Bindal","year":"2019","journal-title":"Journal of Clinical Neuroscience"},{"key":"2025082702075698000_14.5.e242225.9","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1995.82.6.0924"},{"key":"2025082702075698000_14.5.e242225.10","first-page":"597","article-title":"Preservation of cranial nerve function after radiosurgery for nonacoustic schwannomas","volume":"33","author":"Pollock","year":"1993","journal-title":"Neurosurgery"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-242225","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T09:08:02Z","timestamp":1756285682000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-242225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":10,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,5,26]]},"published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1136\/bcr-2021-242225"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-242225","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}