{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,29]],"date-time":"2026-03-29T10:49:13Z","timestamp":1774781353488,"version":"3.50.1"},"reference-count":12,"publisher":"BMJ","issue":"8","license":[{"start":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T00:00:00Z","timestamp":1628640000000},"content-version":"unspecified","delay-in-days":10,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,7,20]]},"published-print":{"date-parts":[[2021,8]]},"abstract":"<jats:p>Pituitary apoplexy is caused by haemorrhage or infarction of the pituitary gland. Presenting signs and symptoms often include severe headache, visual disturbance, ophthalmoplegia, altered consciousness and impaired pituitary function. The management of pituitary apoplexy has very rarely been described during pregnancy and there is no existing data for further pregnancies of affected women. We present a case of a woman with a recurrent pituitary apoplexy due to haemorrhages in a pituitary adenoma in her third and fourth pregnancies. In both pregnancies, the pituitary apoplexy was managed conservatively, but due to therapy-resistant headaches, a preterm delivery was implemented.<\/jats:p>","DOI":"10.1136\/bcr-2021-242353","type":"journal-article","created":{"date-parts":[[2021,8,11]],"date-time":"2021-08-11T13:00:38Z","timestamp":1628686838000},"page":"e242353","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Recurrent pituitary apoplexy in pregnancy"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3568-2008","authenticated-orcid":false,"given":"Franziska","family":"Geissler","sequence":"first","affiliation":[{"name":"Department of Obstetrics, Women's University Hospital Basel, Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irene","family":"Hoesli","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Women's University Hospital Basel, Basel, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monya","family":"Todesco Bernasconi","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, Women's University Hospital Basel, Basel, Switzerland"},{"name":"Obstetrics and Perinatal Medicine, Cantonal Hospital Aarau, Aarau, Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,8,11]]},"reference":[{"key":"2025082711414011000_14.8.e242353.1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2265.1999.00754.x"},{"key":"2025082711414011000_14.8.e242353.2","doi-asserted-by":"publisher","DOI":"10.1080\/02841859809172152"},{"key":"2025082711414011000_14.8.e242353.3","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-09-0923"},{"key":"2025082711414011000_14.8.e242353.4","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3171\/foc.2004.16.4.7","article-title":"Pituitary tumor apoplexy: characteristics, treatment, and outcomes","volume":"16","author":"Verrees","year":"2004","journal-title":"Neurosurg Focus"},{"key":"2025082711414011000_14.8.e242353.5","doi-asserted-by":"publisher","DOI":"10.1530\/EC-16-0057"},{"key":"2025082711414011000_14.8.e242353.6","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1007\/s11102-006-6598-z","article-title":"Lymphocytic hypophysitis: disease spectrum and approach to diagnosis and therapy","volume":"9","author":"Rivera","year":"2006","journal-title":"Pituitary"},{"key":"2025082711414011000_14.8.e242353.7","doi-asserted-by":"crossref","first-page":"e22","DOI":"10.1016\/j.wneu.2019.01.250","article-title":"Clinical features, magnetic resonance imaging, and treatment experience of 20 patients with lymphocytic hypophysitis in a single center","volume":"127","author":"Zhu","year":"2019","journal-title":"World Neurosurg"},{"key":"2025082711414011000_14.8.e242353.8","doi-asserted-by":"publisher","DOI":"10.1177\/1753495X15598917"},{"key":"2025082711414011000_14.8.e242353.9","doi-asserted-by":"publisher","DOI":"10.1227\/01.neu.0000303191.57178.2a"},{"key":"2025082711414011000_14.8.e242353.10","doi-asserted-by":"crossref","first-page":"716","DOI":"10.1007\/s11102-020-01080-w","article-title":"Pituitary apoplexy associated with acute COVID-19 infection and pregnancy","volume":"23","author":"Chan","year":"2020","journal-title":"Pituitary"},{"key":"2025082711414011000_14.8.e242353.11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2265.2010.03913.x"},{"key":"2025082711414011000_14.8.e242353.12","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1177\/0885066607312992","article-title":"Pituitary tumor apoplexy: a review","volume":"23","author":"Nawar","year":"2008","journal-title":"BMJ Intensive Care Med"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-242353","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T18:41:47Z","timestamp":1756320107000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-242353"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8]]},"references-count":12,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2021,8,11]]},"published-print":{"date-parts":[[2021,8]]}},"alternative-id":["10.1136\/bcr-2021-242353"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-242353","relation":{},"ISSN":["1757-790X"],"issn-type":[{"value":"1757-790X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8]]}}}