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Pulse intravenous methyl prednisolone along with immunosuppressive therapy led to remission of her disease. However, delay in diagnosis as NMO-SD led to visual disability in the left eye. Therefore, in young patients with recurrent optic neuritis and normal brain MRI, it may be prudent to get spinal MRI done to look for TM, even when asymptomatic. In addition, we should keep a low threshold for requesting aquaporin-4 antibody testing in these patients.<\/jats:p>","DOI":"10.1136\/bcr-2021-242402","type":"journal-article","created":{"date-parts":[[2021,8,23]],"date-time":"2021-08-23T12:55:20Z","timestamp":1629723320000},"page":"e242402","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Relapsing neuromyelitis optica in an adolescent girl"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7118-2329","authenticated-orcid":false,"given":"Vinita","family":"Gupta","sequence":"first","affiliation":[{"name":"Ophthalmology, AIIMS Rishikesh, Rishikesh, Uttarakhand, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saurabh","family":"Luthra","sequence":"additional","affiliation":[{"name":"Ophthalmology, Drishti Eye Institute, Dehradun, Uttarakhand, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shrey","family":"Maheshwari","sequence":"additional","affiliation":[{"name":"Ophthalmology, Drishti Eye Institute, Dehradun, Uttarakhand, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shrutanjoy M","family":"Das","sequence":"additional","affiliation":[{"name":"Ophthalmology, Drishti Eye Institute, Dehradun, Uttarakhand, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,8,23]]},"reference":[{"key":"2025082702514092000_14.8.e242402.1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.53.5.1107"},{"key":"2025082702514092000_14.8.e242402.2","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/S0140-6736(02)68218-2","article-title":"On the ophthalmoscopic signs of spinal disease","volume":"1","author":"Allbutt","year":"1870","journal-title":"Lancet"},{"key":"2025082702514092000_14.8.e242402.3","first-page":"1033","article-title":"Myelite subaigue compliquee de neurite optique","volume":"8","author":"Devic","year":"1894","journal-title":"Bull Med"},{"key":"2025082702514092000_14.8.e242402.4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)17551-X"},{"key":"2025082702514092000_14.8.e242402.5","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000216139.44259.74"},{"key":"2025082702514092000_14.8.e242402.6","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(07)70216-8"},{"key":"2025082702514092000_14.8.e242402.7","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000001729"},{"key":"2025082702514092000_14.8.e242402.8","first-page":"11","article-title":"Neuromyelitis optica spectrum disorders","volume":"17","author":"Broadley","year":"2017","journal-title":"ACNR"},{"key":"2025082702514092000_14.8.e242402.9","unstructured":"Lotze TE . 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