{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:02:40Z","timestamp":1756339360798,"version":"3.44.0"},"reference-count":9,"publisher":"BMJ","issue":"4","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,3,21]]},"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:p>Haemorrhage in patients with haemophilia is common after minor trauma but may occur spontaneously. Despite the diversity of bleeding sites, spontaneous haemothorax, on a non-traumatic basis, is an exceedingly rare event and only a few cases had been reported. We present a case of a 43-year-old man with a history of haemophilia A who had pleuritic chest pain for 1 day without significant history of trauma. Diagnostic thoracentesis showed bloody pleural fluid in which neither abnormal cell nor organism was found. He was treated by cryoprecipitate replacement and therapeutic thoracentesis for releasing haemothorax. After discharge, the patient returned for follow-up with complete radiological resolution. Regarding the consequences of retained haemothorax from conservative approach and the procedure-related bleeding of given therapeutic intervention in haemothorax making its management in patients with haemophilia to be more challenging. Our case illustrates a conservative treatment of spontaneous haemothorax in patient with haemophilia resulting in a good clinical outcome.<\/jats:p>","DOI":"10.1136\/bcr-2021-242412","type":"journal-article","created":{"date-parts":[[2021,4,7]],"date-time":"2021-04-07T13:33:46Z","timestamp":1617802426000},"page":"e242412","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["A rare case of spontaneous haemothorax in patient with haemophilia A"],"prefix":"10.1136","volume":"14","author":[{"given":"Suthaphong","family":"Tripoppoom","sequence":"first","affiliation":[{"name":"Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7864-3415","authenticated-orcid":false,"given":"Nophol","family":"Leelayuwatanakul","sequence":"additional","affiliation":[{"name":"Division of Pulmonary and Critical Care Medicine, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,4,7]]},"reference":[{"key":"2025082700161320000_14.4.e242412.1","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1097\/00007611-197202000-00007","article-title":"Hemomediastinum and hemothorax in mild hemophilia","volume":"65","author":"Bart","year":"1972","journal-title":"South Med J"},{"key":"2025082700161320000_14.4.e242412.2","doi-asserted-by":"crossref","first-page":"152","DOI":"10.7326\/0003-4819-47-1-152","article-title":"Spontaneous hemothorax in hemophilia: case report and discussion of the hemophilia syndromes, with remarks on the management of hemothorax","volume":"47","author":"Kay","year":"1957","journal-title":"Ann Intern Med"},{"key":"2025082700161320000_14.4.e242412.3","doi-asserted-by":"publisher","DOI":"10.1159\/000096018"},{"key":"2025082700161320000_14.4.e242412.4","first-page":"289","article-title":"Successful treatment of a spontaneous haemothorax with recombinant factor VIIa in a haemophilic child with inhibitors","volume":"14","author":"Gidaris","year":"2010","journal-title":"Hippokratia"},{"key":"2025082700161320000_14.4.e242412.5","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1111\/j.1365-2516.2010.02209.x","article-title":"Haemothorax in children with congenital coagulopathy","volume":"16","author":"Obitko-Pludowska","year":"2010","journal-title":"Haemophilia"},{"key":"2025082700161320000_14.4.e242412.6","unstructured":"Peyman Eshghi ZK , Malek F , Habibpanah B . Massive spontaneous hemothorax in a child with hemophilia. Iranian Journal of Blood & Cancer 2019."},{"key":"2025082700161320000_14.4.e242412.7","doi-asserted-by":"publisher","DOI":"10.1136\/thx.20.5.416"},{"key":"2025082700161320000_14.4.e242412.8","doi-asserted-by":"publisher","DOI":"10.1136\/thx.31.5.601"},{"key":"2025082700161320000_14.4.e242412.9","doi-asserted-by":"crossref","unstructured":"Chiumello D , Coppola S . Oxford textbook of critical care. Management of pleural effusion and haemothorax: Oxford University Press, 2016.","DOI":"10.1093\/med\/9780199600830.003.0125"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-242412","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T07:16:24Z","timestamp":1756278984000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-242412"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":9,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2021,4,7]]},"published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1136\/bcr-2021-242412"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-242412","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2021,4]]}}}