{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T13:01:53Z","timestamp":1760101313328,"version":"3.44.0"},"reference-count":16,"publisher":"BMJ","issue":"5","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,5,14]]},"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:p>A 13-year-old male asthmatic presented to the general paediatric clinic with papilloedema identified following a check-up with his optician due to blurred vision. His asthma was well controlled on a moderate dose of inhaled corticosteroid and there had been no recent increase or decrease in the dose. A diagnosis of benign intracranial hypertension (BIH) was made based on a raised cerebrospinal fluid opening pressure, papilloedema, a normal neurological examination and normal neuroimaging. The only associated risk factor was his inhaled corticosteroids. He was commenced on acetazolamide and the inhaled corticosteroid dose was reduced, resulting in resolution of his papilloedema. This case serves to highlight that steroid side effects including BIH may occur at moderate doses of inhaled corticosteroids and that inhaled corticosteroid dose should be regularly reviewed and decreased to the lowest dose that maintains asthma control.<\/jats:p>","DOI":"10.1136\/bcr-2021-242455","type":"journal-article","created":{"date-parts":[[2021,5,26]],"date-time":"2021-05-26T14:38:53Z","timestamp":1622039933000},"page":"e242455","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Benign intracranial hypertension associated with inhaled corticosteroids in a child with asthma"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9998-9976","authenticated-orcid":false,"given":"James","family":"Trayer","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Children's Health Ireland at Tallaght University Hospital, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Declan","family":"O'Rourke","sequence":"additional","affiliation":[{"name":"Department of Neurology, Children's Health Ireland at Temple Street, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorraine","family":"Cassidy","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Royal Victoria Eye and Ear Hospital Dublin, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Basil","family":"Elnazir","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Children's Health Ireland at Tallaght University Hospital, Dublin, Ireland"},{"name":"Faculty of Health Sciences, Trinity College Dublin, Dublin, Ireland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,5,26]]},"reference":[{"key":"2025082708073512000_14.5.e242455.1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182a55f17"},{"key":"2025082708073512000_14.5.e242455.2","first-page":"223-32","article-title":"Idiopathic intracranial hypertension, hormones, and 11\u03b2-hydroxysteroid dehydrogenases","volume":"9","author":"Markey","year":"2016","journal-title":"J Pain Res"},{"key":"2025082708073512000_14.5.e242455.3","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.57.665.181"},{"key":"2025082708073512000_14.5.e242455.4","doi-asserted-by":"publisher","DOI":"10.1136\/adc.46.249.651"},{"key":"2025082708073512000_14.5.e242455.5","doi-asserted-by":"publisher","DOI":"10.1136\/gut.35.3.423"},{"key":"2025082708073512000_14.5.e242455.6","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.322.7291.897"},{"key":"2025082708073512000_14.5.e242455.7","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.1.6112.550"},{"key":"2025082708073512000_14.5.e242455.8","doi-asserted-by":"crossref","first-page":"3435","DOI":"10.1177\/0300060519857852","article-title":"Pseudotumor cerebri induced by topical application of steroid: a case report","volume":"47","author":"Mohammad","year":"2019","journal-title":"J Int Med Res"},{"key":"2025082708073512000_14.5.e242455.9","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1542\/peds.23.6.1143","article-title":"Occurrence of pseudotumor cerebri (benign intracranial hypertension) during treatment of children with asthma by adrenal steroids; report of three cases","volume":"23","author":"Dees","year":"1959","journal-title":"Pediatrics"},{"key":"2025082708073512000_14.5.e242455.10","first-page":"2050313X1775378","article-title":"Idiopathic intracranial hypertension as a presenting sign of adrenal insufficiency","volume":"6","author":"Shenouda","year":"2018","journal-title":"SAGE Open Med Case Rep"},{"key":"2025082708073512000_14.5.e242455.11","doi-asserted-by":"crossref","first-page":"279","DOI":"10.5694\/j.1326-5377.2006.tb00561.x","article-title":"Inhaled corticosteroids, adrenal suppression and benign intracranial hypertension","volume":"185","author":"Patradoon-Ho","year":"2006","journal-title":"Med J Aust"},{"key":"2025082708073512000_14.5.e242455.12","doi-asserted-by":"crossref","DOI":"10.1542\/peds.2015-2091","article-title":"Presumed pseudotumor cerebri syndrome after withdrawal of inhaled glucocorticoids","volume":"137","author":"Kwon","year":"2016","journal-title":"Pediatrics"},{"key":"2025082708073512000_14.5.e242455.13","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.anai.2016.10.002","article-title":"Adrenal insufficiency associated with long-term use of inhaled steroid in asthma","volume":"118","author":"Choi","year":"2017","journal-title":"Ann Allergy Asthma Immunol"},{"key":"2025082708073512000_14.5.e242455.14","unstructured":"Global Initiative for Asthma . Global strategy for asthma management and prevention, 2019."},{"key":"2025082708073512000_14.5.e242455.15","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2015-310145"},{"key":"2025082708073512000_14.5.e242455.16","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(98)70007-7"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2021-242455","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:07:45Z","timestamp":1756307265000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2021-242455"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":16,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2021,5,26]]},"published-print":{"date-parts":[[2021,5]]}},"alternative-id":["10.1136\/bcr-2021-242455"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2021-242455","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2021,5]]}}}