{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T19:42:58Z","timestamp":1788637378217,"version":"build-2803163510"},"reference-count":12,"publisher":"BMJ","issue":"5","funder":[{"DOI":"10.13039\/501100005809","name":"Hyderabad Eye Research Foundation","doi-asserted-by":"publisher","award":["LEC BHR-R-03-21-597"],"award-info":[{"award-number":["LEC BHR-R-03-21-597"]}],"id":[{"id":"10.13039\/501100005809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,4,29]]},"published-print":{"date-parts":[[2021,5]]},"abstract":"<jats:p>We report a rare presentation of xerophthalmia due to partial pancreatic exocrine insufficiency following Frey\u2019s surgery (pancreatic resection) in a 12-year-old girl. The child had undergone this surgery for chronic calcific pancreatitis 3\u2009years before and presented with ocular irritation and decreased vision of 3\u2009months duration. Ocular examination showed severe conjunctival and corneal xerosis. Her serum retinol levels and 25-hydroxyvitamin D were tested and were extremely low. The condition rapidly reversed following high-dose replacement therapy with vitamin A and D. This case highlights the importance of continuous enzyme replacement therapy as well as dietary modification and nutritional supplement therapy and monitoring of ocular symptoms in post-pancreatic surgery.<\/jats:p>","DOI":"10.1136\/bcr-2021-242710","type":"journal-article","created":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T11:56:13Z","timestamp":1621857373000},"page":"e242710","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Xerophthalmia due to vitamin A deficiency following Frey\u2019s procedure for chronic calcific pancreatitis"],"prefix":"10.1136","volume":"14","author":[{"given":"Supriya","family":"Sharma","sequence":"first","affiliation":[{"name":"GPR-ICARE, LV Prasad Eye Institute, Hyderabad, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8696-9669","authenticated-orcid":false,"given":"Somasheila 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