{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:03:44Z","timestamp":1756339424587,"version":"3.44.0"},"reference-count":20,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,6,17]]},"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:p>Jaundice is one of the most common situations during the neonatal period. Alloimmune haemolytic disease of the fetus and newborn (AHDFN) is a major cause of pathological jaundice during the neonatal period. Since the establishment of anti-D prophylaxis, other antigens have gained greater clinical importance. The maternal antierythrocyte antibody screen is of great importance in monitoring pregnancy and in predicting the risk of AHDFN. A positive result should alert to the possibility of AHDFN and promote close surveillance of fetal anaemia, as well as neonatal anaemia and hyperbilirubinaemia. We describe a case of AHDFN due to incompatibility of the Rhesus c (Rhc) subgroup, diagnosed in pregnancy, but without effective transmission of information in the perinatal period, so a positive maternal antierythrocyte antibody screen was missed. This case highlights the importance of non-RhD antigens in this disease, but also the importance of a successful handoff of information in the delivery room.<\/jats:p>","DOI":"10.1136\/bcr-2021-242731","type":"journal-article","created":{"date-parts":[[2021,7,12]],"date-time":"2021-07-12T12:34:02Z","timestamp":1626093242000},"page":"e242731","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Haemolytic disease of the fetus and newborn: do not miss a positive maternal antierythrocyte antibody screen"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2230-6214","authenticated-orcid":false,"given":"Nuno","family":"Serra de Almeida","sequence":"first","affiliation":[{"name":"Pediatric Department, Centro Hospitalar Tondela Viseu, EPE, Viseu, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0877-214X","authenticated-orcid":false,"given":"Crisbety","family":"Pinho","sequence":"additional","affiliation":[{"name":"Pediatric Department, Centro Hospitalar e Universit\u00e1rio de Coimbra, EPE, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diogo","family":"Faim","sequence":"additional","affiliation":[{"name":"Pediatric Department, Centro Hospitalar e Universit\u00e1rio de Coimbra, EPE, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel","family":"Henriques","sequence":"additional","affiliation":[{"name":"Department of Neonatology, Maternidade Doutor Daniel de Matos, Centro Hospitalar e Universit\u00e1rio de Coimbra, EPE, Coimbra, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,7,12]]},"reference":[{"key":"2025082703263526000_14.7.e242731.1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.114.1.297"},{"key":"2025082703263526000_14.7.e242731.2","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0b013e31822c9b4c"},{"key":"2025082703263526000_14.7.e242731.3","first-page":"484","article-title":"Improving the management and outcome in haemolytic disease of the foetus and newborn","volume":"11","author":"Lopriore","year":"2013","journal-title":"Blood Transfus"},{"key":"2025082703263526000_14.7.e242731.4","doi-asserted-by":"publisher","DOI":"10.1182\/asheducation-2015.1.146"},{"key":"2025082703263526000_14.7.e242731.5","unstructured":"Dean L . 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