{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T07:14:16Z","timestamp":1761808456763,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"6","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,5,30]]},"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:p>We present the case of a 48-year-old man with a background of well-controlled HIV who presented with bony pain in multiple regions and raised inflammatory markers. After an investigative process, the patient was newly diagnosed with secondary syphilis. Bony pain, secondary to osteolytic lesions and demonstrated on plain radiography, CT and nuclear medicine imaging, was the sole presenting feature. The patient was successfully treated with penicillin G and his symptoms improved. Rheumatologists are often tasked with diagnosing the cause of a patient\u2019s pain. However, in this case, a multidisciplinary approach was needed and the contribution of a specialist in Genitourinary Medicine\/HIV was required to help diagnose this rare cause of bony pain.<\/jats:p>","DOI":"10.1136\/bcr-2021-242814","type":"journal-article","created":{"date-parts":[[2021,6,22]],"date-time":"2021-06-22T12:04:14Z","timestamp":1624363454000},"page":"e242814","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Osteolytic lesions as the sole presenting feature of secondary syphilis"],"prefix":"10.1136","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6736-5678","authenticated-orcid":false,"given":"Matthew","family":"Colquhoun","sequence":"first","affiliation":[{"name":"Rheumatology, Northwick Park Hospital, Harrow, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Othman","family":"Kirresh","sequence":"additional","affiliation":[{"name":"Rheumatology, West Middlesex University Hospital, Isleworth, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad","family":"Keikha","sequence":"additional","affiliation":[{"name":"Radiology, West Middlesex Hospital, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lewis","family":"Haddow","sequence":"additional","affiliation":[{"name":"HIV and Genitourinary Medicine, Kingston Hospital NHS Foundation Trust, Kingston upon Thames, London, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2021,6,22]]},"reference":[{"key":"2025082801022263000_14.6.e242814.1","unstructured":"Public Health England . Addressing the increase in syphilis in England: Phe action plan. 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