{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T19:08:33Z","timestamp":1775156913038,"version":"3.50.1"},"reference-count":17,"publisher":"BMJ","issue":"3","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2022,2,10]]},"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:p>Acute leukaemia is the most common childhood cancer. The clinical presentation of acute leukaemia includes fever, pallor, bleeding tendencies, hepatosplenomegaly, lymphadenopathy and bone pains. This case is about a 7-year-old boy who presented with 2\u2009months of progressive low back pain after jumping into the sea. Radiologic workup showed compression fractures in the T6\u2013L5 regions of the spine. Trauma and osteogenesis imperfecta were considered initially until the patient developed the classic features of leukaemia. Analysis of the bone marrow aspirate, 2 months after the sea incident, revealed B cell acute lymphoblastic leukaemia (ALL). The low back pain subsided after a week of chemotherapy. A symptom that involves bone pain in a child needs thorough evaluation because a delay in diagnosis affects the outcome of treatment. ALL has been lingering at the time of his accident and this has caused weakening of his spine that resulted in much more severe injury than would have occurred in the absence of the ALL.<\/jats:p>","DOI":"10.1136\/bcr-2021-242843","type":"journal-article","created":{"date-parts":[[2022,3,4]],"date-time":"2022-03-04T11:10:55Z","timestamp":1646392255000},"page":"e242843","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Low back pain as an unusual presentation in a child with acute lymphoblastic leukaemia"],"prefix":"10.1136","volume":"15","author":[{"given":"Daisy Olave","family":"Sanchez-Mostiero","sequence":"first","affiliation":[{"name":"Department of Clinical Epidemiology, University of the Philippines, Manila, Philippines"},{"name":"Department of Pediatrics, Batangas Medical Center, Batangas, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jamela Merriam Aragon","family":"Boussati","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Batangas Medical Center, Batangas, Philippines"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2022,3,4]]},"reference":[{"key":"2025082709125450000_15.3.e242843.1","doi-asserted-by":"publisher","DOI":"10.1097\/BPO.0b13e31815ff350"},{"key":"2025082709125450000_15.3.e242843.2","doi-asserted-by":"publisher","DOI":"10.1053\/sarh.2000.5752"},{"key":"2025082709125450000_15.3.e242843.3","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.40.4830"},{"key":"2025082709125450000_15.3.e242843.4","doi-asserted-by":"crossref","first-page":"434","DOI":"10.4103\/2249-4863.220014","article-title":"Low backache in adults as an initial presentation of acute lymphoblastic leukemia","volume":"6","author":"Garg","year":"2017","journal-title":"J Family Med Prim Care"},{"key":"2025082709125450000_15.3.e242843.5","doi-asserted-by":"crossref","first-page":"657","DOI":"10.4103\/2249-4863.222020","article-title":"Back pain: An unusual manifestation of acute lymphoblastic leukemia - 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